Time elapsed between Zika and dengue virus infections affects antibody and T cell responses

Here, the authors show that the time elapsed between Zika infection and subsequent dengue virus infection affects the magnitude and durability of the antibody and cell-mediated immune responses against dengue virus, but not viremia. This research in non-human primates has implications for co-endemic...

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Autores principales:	Erick X. Pérez-Guzmán, Petraleigh Pantoja, Crisanta Serrano-Collazo, Mariah A. Hassert, Alexandra Ortiz-Rosa, Idia V. Rodríguez, Luis Giavedoni, Vida Hodara, Laura Parodi, Lorna Cruz, Teresa Arana, Laura J. White, Melween I. Martínez, Daniela Weiskopf, James D. Brien, Aravinda de Silva, Amelia K. Pinto, Carlos A. Sariol
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/df47fefed1b64aed9ca8592422e25d1d
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spelling	oai:doaj.org-article:df47fefed1b64aed9ca8592422e25d1d2021-12-02T17:31:21ZTime elapsed between Zika and dengue virus infections affects antibody and T cell responses10.1038/s41467-019-12295-22041-1723https://doaj.org/article/df47fefed1b64aed9ca8592422e25d1d2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12295-2https://doaj.org/toc/2041-1723Here, the authors show that the time elapsed between Zika infection and subsequent dengue virus infection affects the magnitude and durability of the antibody and cell-mediated immune responses against dengue virus, but not viremia. This research in non-human primates has implications for co-endemic regions and vaccination.Erick X. Pérez-GuzmánPetraleigh PantojaCrisanta Serrano-CollazoMariah A. HassertAlexandra Ortiz-RosaIdia V. RodríguezLuis GiavedoniVida HodaraLaura ParodiLorna CruzTeresa AranaLaura J. WhiteMelween I. MartínezDaniela WeiskopfJames D. BrienAravinda de SilvaAmelia K. PintoCarlos A. SariolNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erick X. Pérez-Guzmán Petraleigh Pantoja Crisanta Serrano-Collazo Mariah A. Hassert Alexandra Ortiz-Rosa Idia V. Rodríguez Luis Giavedoni Vida Hodara Laura Parodi Lorna Cruz Teresa Arana Laura J. White Melween I. Martínez Daniela Weiskopf James D. Brien Aravinda de Silva Amelia K. Pinto Carlos A. Sariol Time elapsed between Zika and dengue virus infections affects antibody and T cell responses
description	Here, the authors show that the time elapsed between Zika infection and subsequent dengue virus infection affects the magnitude and durability of the antibody and cell-mediated immune responses against dengue virus, but not viremia. This research in non-human primates has implications for co-endemic regions and vaccination.
format	article
author	Erick X. Pérez-Guzmán Petraleigh Pantoja Crisanta Serrano-Collazo Mariah A. Hassert Alexandra Ortiz-Rosa Idia V. Rodríguez Luis Giavedoni Vida Hodara Laura Parodi Lorna Cruz Teresa Arana Laura J. White Melween I. Martínez Daniela Weiskopf James D. Brien Aravinda de Silva Amelia K. Pinto Carlos A. Sariol
author_facet	Erick X. Pérez-Guzmán Petraleigh Pantoja Crisanta Serrano-Collazo Mariah A. Hassert Alexandra Ortiz-Rosa Idia V. Rodríguez Luis Giavedoni Vida Hodara Laura Parodi Lorna Cruz Teresa Arana Laura J. White Melween I. Martínez Daniela Weiskopf James D. Brien Aravinda de Silva Amelia K. Pinto Carlos A. Sariol
author_sort	Erick X. Pérez-Guzmán
title	Time elapsed between Zika and dengue virus infections affects antibody and T cell responses
title_short	Time elapsed between Zika and dengue virus infections affects antibody and T cell responses
title_full	Time elapsed between Zika and dengue virus infections affects antibody and T cell responses
title_fullStr	Time elapsed between Zika and dengue virus infections affects antibody and T cell responses
title_full_unstemmed	Time elapsed between Zika and dengue virus infections affects antibody and T cell responses
title_sort	time elapsed between zika and dengue virus infections affects antibody and t cell responses
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/df47fefed1b64aed9ca8592422e25d1d
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Time elapsed between Zika and dengue virus infections affects antibody and T cell responses

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