Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

Abstract The peptide HsTX1[R14A] is a potent and selective blocker of the voltage-gated potassium channel Kv1.3, which is a highly promising target for the treatment of autoimmune diseases and other conditions. In order to assess the biodistribution of this peptide, it was conjugated with NOTA and r...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ralf Bergmann, Manja Kubeil, Kristof Zarschler, Sandeep Chhabra, Rajeev B. Tajhya, Christine Beeton, Michael W. Pennington, Michael Bachmann, Raymond S. Norton, Holger Stephan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/df49b90ff84b43d9acf32897f9f258e4
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares