Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

Abstract The peptide HsTX1[R14A] is a potent and selective blocker of the voltage-gated potassium channel Kv1.3, which is a highly promising target for the treatment of autoimmune diseases and other conditions. In order to assess the biodistribution of this peptide, it was conjugated with NOTA and r...

Full description

Saved in:
Bibliographic Details
Main Authors: Ralf Bergmann, Manja Kubeil, Kristof Zarschler, Sandeep Chhabra, Rajeev B. Tajhya, Christine Beeton, Michael W. Pennington, Michael Bachmann, Raymond S. Norton, Holger Stephan
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/df49b90ff84b43d9acf32897f9f258e4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items