Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment

Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment

Abstract Transforming growth factor (TGF)-β1 contributes to autocrine and paracrine functions in the tumor microenvironment (TME). The present study examined the effects of TGF-β1 crosstalk in TME and its role in mediating tumor formation and progression by targeted abrogation of TGF-β1 expression i...

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Autores principales: Lakisha D. Moore-Smith, Tatyana Isayeva, Joo Hyoung Lee, Andra Frost, Selvarangan Ponnazhagan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/df50d61f90da4eb596f8bb21be034591
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