Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment

Abstract Transforming growth factor (TGF)-β1 contributes to autocrine and paracrine functions in the tumor microenvironment (TME). The present study examined the effects of TGF-β1 crosstalk in TME and its role in mediating tumor formation and progression by targeted abrogation of TGF-β1 expression i...

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Bibliographic Details
Main Authors: Lakisha D. Moore-Smith, Tatyana Isayeva, Joo Hyoung Lee, Andra Frost, Selvarangan Ponnazhagan
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/df50d61f90da4eb596f8bb21be034591
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