Homeostatic plasticity shapes the visual system’s first synapse

Retinal rod bipolar cells (RBCs) partially undergo programmed cell death triggering cell density-dependent plasticity. This study shows that increased removal of RBCs using genetic approaches causes dendrites of the remaining RBCs to expand and contact more rod photoreceptors while reducing connecti...

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Auteurs principaux:	Robert E. Johnson, Nai-Wen Tien, Ning Shen, James T. Pearson, Florentina Soto, Daniel Kerschensteiner
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/df5db3a28cba4574a1aff19ad4a1cf8d
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spelling	oai:doaj.org-article:df5db3a28cba4574a1aff19ad4a1cf8d2021-12-02T17:01:25ZHomeostatic plasticity shapes the visual system’s first synapse10.1038/s41467-017-01332-72041-1723https://doaj.org/article/df5db3a28cba4574a1aff19ad4a1cf8d2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01332-7https://doaj.org/toc/2041-1723Retinal rod bipolar cells (RBCs) partially undergo programmed cell death triggering cell density-dependent plasticity. This study shows that increased removal of RBCs using genetic approaches causes dendrites of the remaining RBCs to expand and contact more rod photoreceptors while reducing connectivity with each.Robert E. JohnsonNai-Wen TienNing ShenJames T. PearsonFlorentina SotoDaniel KerschensteinerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Robert E. Johnson Nai-Wen Tien Ning Shen James T. Pearson Florentina Soto Daniel Kerschensteiner Homeostatic plasticity shapes the visual system’s first synapse
description	Retinal rod bipolar cells (RBCs) partially undergo programmed cell death triggering cell density-dependent plasticity. This study shows that increased removal of RBCs using genetic approaches causes dendrites of the remaining RBCs to expand and contact more rod photoreceptors while reducing connectivity with each.
format	article
author	Robert E. Johnson Nai-Wen Tien Ning Shen James T. Pearson Florentina Soto Daniel Kerschensteiner
author_facet	Robert E. Johnson Nai-Wen Tien Ning Shen James T. Pearson Florentina Soto Daniel Kerschensteiner
author_sort	Robert E. Johnson
title	Homeostatic plasticity shapes the visual system’s first synapse
title_short	Homeostatic plasticity shapes the visual system’s first synapse
title_full	Homeostatic plasticity shapes the visual system’s first synapse
title_fullStr	Homeostatic plasticity shapes the visual system’s first synapse
title_full_unstemmed	Homeostatic plasticity shapes the visual system’s first synapse
title_sort	homeostatic plasticity shapes the visual system’s first synapse
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/df5db3a28cba4574a1aff19ad4a1cf8d
work_keys_str_mv	AT robertejohnson homeostaticplasticityshapesthevisualsystemsfirstsynapse AT naiwentien homeostaticplasticityshapesthevisualsystemsfirstsynapse AT ningshen homeostaticplasticityshapesthevisualsystemsfirstsynapse AT jamestpearson homeostaticplasticityshapesthevisualsystemsfirstsynapse AT florentinasoto homeostaticplasticityshapesthevisualsystemsfirstsynapse AT danielkerschensteiner homeostaticplasticityshapesthevisualsystemsfirstsynapse
_version_	1718382182062358528

Homeostatic plasticity shapes the visual system’s first synapse

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