Homeostatic plasticity shapes the visual system’s first synapse

Retinal rod bipolar cells (RBCs) partially undergo programmed cell death triggering cell density-dependent plasticity. This study shows that increased removal of RBCs using genetic approaches causes dendrites of the remaining RBCs to expand and contact more rod photoreceptors while reducing connecti...

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Autores principales: Robert E. Johnson, Nai-Wen Tien, Ning Shen, James T. Pearson, Florentina Soto, Daniel Kerschensteiner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/df5db3a28cba4574a1aff19ad4a1cf8d
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spelling oai:doaj.org-article:df5db3a28cba4574a1aff19ad4a1cf8d2021-12-02T17:01:25ZHomeostatic plasticity shapes the visual system’s first synapse10.1038/s41467-017-01332-72041-1723https://doaj.org/article/df5db3a28cba4574a1aff19ad4a1cf8d2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01332-7https://doaj.org/toc/2041-1723Retinal rod bipolar cells (RBCs) partially undergo programmed cell death triggering cell density-dependent plasticity. This study shows that increased removal of RBCs using genetic approaches causes dendrites of the remaining RBCs to expand and contact more rod photoreceptors while reducing connectivity with each.Robert E. JohnsonNai-Wen TienNing ShenJames T. PearsonFlorentina SotoDaniel KerschensteinerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Robert E. Johnson
Nai-Wen Tien
Ning Shen
James T. Pearson
Florentina Soto
Daniel Kerschensteiner
Homeostatic plasticity shapes the visual system’s first synapse
description Retinal rod bipolar cells (RBCs) partially undergo programmed cell death triggering cell density-dependent plasticity. This study shows that increased removal of RBCs using genetic approaches causes dendrites of the remaining RBCs to expand and contact more rod photoreceptors while reducing connectivity with each.
format article
author Robert E. Johnson
Nai-Wen Tien
Ning Shen
James T. Pearson
Florentina Soto
Daniel Kerschensteiner
author_facet Robert E. Johnson
Nai-Wen Tien
Ning Shen
James T. Pearson
Florentina Soto
Daniel Kerschensteiner
author_sort Robert E. Johnson
title Homeostatic plasticity shapes the visual system’s first synapse
title_short Homeostatic plasticity shapes the visual system’s first synapse
title_full Homeostatic plasticity shapes the visual system’s first synapse
title_fullStr Homeostatic plasticity shapes the visual system’s first synapse
title_full_unstemmed Homeostatic plasticity shapes the visual system’s first synapse
title_sort homeostatic plasticity shapes the visual system’s first synapse
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/df5db3a28cba4574a1aff19ad4a1cf8d
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AT ningshen homeostaticplasticityshapesthevisualsystemsfirstsynapse
AT jamestpearson homeostaticplasticityshapesthevisualsystemsfirstsynapse
AT florentinasoto homeostaticplasticityshapesthevisualsystemsfirstsynapse
AT danielkerschensteiner homeostaticplasticityshapesthevisualsystemsfirstsynapse
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