Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching

Abstract To analyze the relationship between systemic lipid profile levels and meibomian gland dysfunction (MGD) subtype in Korea. The ophthalmic data of 95 eyes and the serum lipid profiles of 95 patients were reviewed. These factors were compared with those of the general population using data fro...

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Autores principales:	Minji Ha, Jiyun Song, Sunkyoung Park, Kyungdo Han, Ho Sik Hwang, Hyun-Seung Kim, Reiko Arita, Kyung-Sun Na
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/df5fe68e587746abb7a8ccd68b489f24
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spelling	oai:doaj.org-article:df5fe68e587746abb7a8ccd68b489f242021-12-02T16:28:50ZRelationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching10.1038/s41598-021-95599-y2045-2322https://doaj.org/article/df5fe68e587746abb7a8ccd68b489f242021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95599-yhttps://doaj.org/toc/2045-2322Abstract To analyze the relationship between systemic lipid profile levels and meibomian gland dysfunction (MGD) subtype in Korea. The ophthalmic data of 95 eyes and the serum lipid profiles of 95 patients were reviewed. These factors were compared with those of the general population using data from the Korean National Health and Nutrition Examination Survey (KNHANES), which evaluated 2,917 subjects. Of these, the comparison group (1:5 ratio; n = 475) was selected using propensity score matching according to age and sex. In addition, we analyzed the relationship between serum lipid profile levels and MGD subtypes in MGD patients. The mean high-density lipoprotein (HDL) value of the MGD patients was significantly higher than that of the general population (P < 0.0001). Moreover, the mean low-density lipoprotein (LDL) levels of the MGD patients was significantly lower than that of the general population (P = 0.0002). However, the mean total cholesterol (TC), and triglyceride (TG) levels of the MGD patients were not significantly different from those of the general population (TC: P = 0.4282, TG: P = 0.5613). In addition, no serum lipid levels statistically differed among the MGD subtypes (TC: P = 0.7650, HDL: P = 0.2480, LDL: P = 0.3430, TG: P = 0.7030). A statistically significant increase in HDL and decrease in LDL concentration were observed in the MGD group, although there was no difference in any serum lipid level among the MGD subtypes.Minji HaJiyun SongSunkyoung ParkKyungdo HanHo Sik HwangHyun-Seung KimReiko AritaKyung-Sun NaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Minji Ha Jiyun Song Sunkyoung Park Kyungdo Han Ho Sik Hwang Hyun-Seung Kim Reiko Arita Kyung-Sun Na Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching
description	Abstract To analyze the relationship between systemic lipid profile levels and meibomian gland dysfunction (MGD) subtype in Korea. The ophthalmic data of 95 eyes and the serum lipid profiles of 95 patients were reviewed. These factors were compared with those of the general population using data from the Korean National Health and Nutrition Examination Survey (KNHANES), which evaluated 2,917 subjects. Of these, the comparison group (1:5 ratio; n = 475) was selected using propensity score matching according to age and sex. In addition, we analyzed the relationship between serum lipid profile levels and MGD subtypes in MGD patients. The mean high-density lipoprotein (HDL) value of the MGD patients was significantly higher than that of the general population (P < 0.0001). Moreover, the mean low-density lipoprotein (LDL) levels of the MGD patients was significantly lower than that of the general population (P = 0.0002). However, the mean total cholesterol (TC), and triglyceride (TG) levels of the MGD patients were not significantly different from those of the general population (TC: P = 0.4282, TG: P = 0.5613). In addition, no serum lipid levels statistically differed among the MGD subtypes (TC: P = 0.7650, HDL: P = 0.2480, LDL: P = 0.3430, TG: P = 0.7030). A statistically significant increase in HDL and decrease in LDL concentration were observed in the MGD group, although there was no difference in any serum lipid level among the MGD subtypes.
format	article
author	Minji Ha Jiyun Song Sunkyoung Park Kyungdo Han Ho Sik Hwang Hyun-Seung Kim Reiko Arita Kyung-Sun Na
author_facet	Minji Ha Jiyun Song Sunkyoung Park Kyungdo Han Ho Sik Hwang Hyun-Seung Kim Reiko Arita Kyung-Sun Na
author_sort	Minji Ha
title	Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching
title_short	Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching
title_full	Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching
title_fullStr	Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching
title_full_unstemmed	Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching
title_sort	relationship between serum lipid level and meibomian gland dysfunction subtype in korea using propensity score matching
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/df5fe68e587746abb7a8ccd68b489f24
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Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching

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