Multiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering

The recent improvements in diagnosis enabled by advances in liquid biopsy and oncological imaging significantly better cancer care. Both these complementary approaches, which are used for early tumor detection, characterization, and monitoring, can benefit from applying techniques based on surface-e...

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Autor principal: Francesco Dell’Olio
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Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/df64066034be49698928ee5d63e5d705
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spelling oai:doaj.org-article:df64066034be49698928ee5d63e5d7052021-11-25T16:55:33ZMultiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering10.3390/bios111104492079-6374https://doaj.org/article/df64066034be49698928ee5d63e5d7052021-11-01T00:00:00Zhttps://www.mdpi.com/2079-6374/11/11/449https://doaj.org/toc/2079-6374The recent improvements in diagnosis enabled by advances in liquid biopsy and oncological imaging significantly better cancer care. Both these complementary approaches, which are used for early tumor detection, characterization, and monitoring, can benefit from applying techniques based on surface-enhanced Raman scattering (SERS). With a detection sensitivity at the single-molecule level, SERS spectroscopy is widely used in cell and molecular biology, and its capability for the in vitro detection of several types of cancer biomarkers is well established. In the last few years, several intriguing SERS applications have emerged, including in vivo imaging for tumor targeting and the monitoring of drug release. In this paper, selected recent developments and trends in SERS applications in the field of liquid biopsy and tumor imaging are critically reviewed, with a special emphasis on results that demonstrate the clinical utility of SERS.Francesco Dell’OlioMDPI AGarticlebiophotonicsbiosensingnanoplasmonicssurface-enhanced Raman scatteringoncologyBiotechnologyTP248.13-248.65ENBiosensors, Vol 11, Iss 449, p 449 (2021)
institution DOAJ
collection DOAJ
language EN
topic biophotonics
biosensing
nanoplasmonics
surface-enhanced Raman scattering
oncology
Biotechnology
TP248.13-248.65
spellingShingle biophotonics
biosensing
nanoplasmonics
surface-enhanced Raman scattering
oncology
Biotechnology
TP248.13-248.65
Francesco Dell’Olio
Multiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering
description The recent improvements in diagnosis enabled by advances in liquid biopsy and oncological imaging significantly better cancer care. Both these complementary approaches, which are used for early tumor detection, characterization, and monitoring, can benefit from applying techniques based on surface-enhanced Raman scattering (SERS). With a detection sensitivity at the single-molecule level, SERS spectroscopy is widely used in cell and molecular biology, and its capability for the in vitro detection of several types of cancer biomarkers is well established. In the last few years, several intriguing SERS applications have emerged, including in vivo imaging for tumor targeting and the monitoring of drug release. In this paper, selected recent developments and trends in SERS applications in the field of liquid biopsy and tumor imaging are critically reviewed, with a special emphasis on results that demonstrate the clinical utility of SERS.
format article
author Francesco Dell’Olio
author_facet Francesco Dell’Olio
author_sort Francesco Dell’Olio
title Multiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering
title_short Multiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering
title_full Multiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering
title_fullStr Multiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering
title_full_unstemmed Multiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering
title_sort multiplexed liquid biopsy and tumor imaging using surface-enhanced raman scattering
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/df64066034be49698928ee5d63e5d705
work_keys_str_mv AT francescodellolio multiplexedliquidbiopsyandtumorimagingusingsurfaceenhancedramanscattering
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