Angiopoietin-like 4 is over-expressed in rheumatoid arthritis patients: association with pathological bone resorption.

Angiopoietin-like 4 is over-expressed in rheumatoid arthritis patients: association with pathological bone resorption.

<h4>Introduction</h4>Osteoclasts are responsible for the bone loss associated with rheumatoid arthritis (RA). The secreted adipokine angiopoietin-like 4 (ANGPTL4) specifically increases osteoclast-mediated bone resorption. We have investigated expression of ANGPTL4 and its regulatory tra...

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Autores principales: Catherine Swales, Nicholas A Athanasou, Helen J Knowles
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/df75ccba4e794687b6ed9f1acbdb6df8
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