Expression and function of PDGF-C in development and stem cells

Platelet-derived growth factor C (PDGF-C) is a relatively new member of the PDGF family, discovered nearly 20 years after the finding of platelet-derived growth factor A (PDGF-A) and platelet-derived growth factor B (PDGF-B). PDGF-C is generally expressed in most organs and cell types. Studies from...

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Autores principales:	Yi Tian, Ying Zhan, Qin Jiang, Weisi Lu, Xuri Li
Formato:	article
Lenguaje:	EN
Publicado:	The Royal Society 2021
Materias:	platelet-derived growth factor C development embryogenesis organogenesis stem cell pluripotency Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/df7cf989c9f540faace8915072f01d44
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spelling	oai:doaj.org-article:df7cf989c9f540faace8915072f01d442021-12-01T08:06:04ZExpression and function of PDGF-C in development and stem cells10.1098/rsob.2102682046-2441https://doaj.org/article/df7cf989c9f540faace8915072f01d442021-12-01T00:00:00Zhttps://royalsocietypublishing.org/doi/10.1098/rsob.210268https://doaj.org/toc/2046-2441Platelet-derived growth factor C (PDGF-C) is a relatively new member of the PDGF family, discovered nearly 20 years after the finding of platelet-derived growth factor A (PDGF-A) and platelet-derived growth factor B (PDGF-B). PDGF-C is generally expressed in most organs and cell types. Studies from the past 20 years have demonstrated critical roles of PDGF-C in numerous biological, physiological and pathological processes, such as development, angiogenesis, tumour growth, tissue remodelling, wound healing, atherosclerosis, fibrosis, stem/progenitor cell regulation and metabolism. Understanding PDGF-C expression and activities thus will be of great importance to various research disciplines. In this review, however, we mainly discuss the expression and functions of PDGF-C and its receptors in development and stem cells.Yi TianYing ZhanQin JiangWeisi LuXuri LiThe Royal Societyarticleplatelet-derived growth factor Cdevelopmentembryogenesisorganogenesisstem cellpluripotencyBiology (General)QH301-705.5ENOpen Biology, Vol 11, Iss 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	platelet-derived growth factor C development embryogenesis organogenesis stem cell pluripotency Biology (General) QH301-705.5
spellingShingle	platelet-derived growth factor C development embryogenesis organogenesis stem cell pluripotency Biology (General) QH301-705.5 Yi Tian Ying Zhan Qin Jiang Weisi Lu Xuri Li Expression and function of PDGF-C in development and stem cells
description	Platelet-derived growth factor C (PDGF-C) is a relatively new member of the PDGF family, discovered nearly 20 years after the finding of platelet-derived growth factor A (PDGF-A) and platelet-derived growth factor B (PDGF-B). PDGF-C is generally expressed in most organs and cell types. Studies from the past 20 years have demonstrated critical roles of PDGF-C in numerous biological, physiological and pathological processes, such as development, angiogenesis, tumour growth, tissue remodelling, wound healing, atherosclerosis, fibrosis, stem/progenitor cell regulation and metabolism. Understanding PDGF-C expression and activities thus will be of great importance to various research disciplines. In this review, however, we mainly discuss the expression and functions of PDGF-C and its receptors in development and stem cells.
format	article
author	Yi Tian Ying Zhan Qin Jiang Weisi Lu Xuri Li
author_facet	Yi Tian Ying Zhan Qin Jiang Weisi Lu Xuri Li
author_sort	Yi Tian
title	Expression and function of PDGF-C in development and stem cells
title_short	Expression and function of PDGF-C in development and stem cells
title_full	Expression and function of PDGF-C in development and stem cells
title_fullStr	Expression and function of PDGF-C in development and stem cells
title_full_unstemmed	Expression and function of PDGF-C in development and stem cells
title_sort	expression and function of pdgf-c in development and stem cells
publisher	The Royal Society
publishDate	2021
url	https://doaj.org/article/df7cf989c9f540faace8915072f01d44
work_keys_str_mv	AT yitian expressionandfunctionofpdgfcindevelopmentandstemcells AT yingzhan expressionandfunctionofpdgfcindevelopmentandstemcells AT qinjiang expressionandfunctionofpdgfcindevelopmentandstemcells AT weisilu expressionandfunctionofpdgfcindevelopmentandstemcells AT xurili expressionandfunctionofpdgfcindevelopmentandstemcells
_version_	1718405447310901248

Expression and function of PDGF-C in development and stem cells

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