Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber

Wael Soliman*, Ehab I Wasfi*, Omar M AliDepartment of Ophthalmology, Assiut University Hospital, Assiut University, Assiut, Egypt*These authors contributed equally to this workAim: To study the morphological pattern of pearl-like lesions in the anterior chambers of children before and after manageme...

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Autores principales:	Soliman W, Wasfi EI, Ali OM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/df7ed69106f04616853e6a850c4c3499
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spelling	oai:doaj.org-article:df7ed69106f04616853e6a850c4c34992021-12-02T06:34:18ZSpectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber1177-54671177-5483https://doaj.org/article/df7ed69106f04616853e6a850c4c34992012-06-01T00:00:00Zhttp://www.dovepress.com/spectral-domain-optical-coherence-tomography-study-of-pearl-like-lesio-a10098https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Wael Soliman, Ehab I Wasfi, Omar M AliDepartment of Ophthalmology, Assiut University Hospital, Assiut University, Assiut, Egypt*These authors contributed equally to this workAim: To study the morphological pattern of pearl-like lesions in the anterior chambers of children before and after management using anterior segment spectral domain optical coherence tomography (SD-OCT).Patients and methods: This was a prospective, observational cross-sectional study of patients presenting with peculiar pearl-like lesions in the anterior chamber of their eyes. 1 mL of betamethasone sodium phosphate (2 mg/mL) and betamethasone dipropionate (5 mg/mL) was injected subconjunctivally. Follow-ups of all patients were conducted for a period of 6 weeks. Anterior segment imaging was done using SD-OCT and also photo slit lamp before and after management.Results: Twelve eyes of 12 patients were included in this study. These patients presented with pearl-like lesions in the anterior chamber with signs of anterior uveitis. There was no history of ocular injury or tuberculosis in any patients. Six weeks after subconjunctival steroid injection, all patients achieved mean best-corrected visual acuity, which changed from 0.2 (range 0.1&ndash;0.4) to 0.5 (range 0.4&ndash;0.8), and the severity of iritis decreased. SD-OCT showed that the lesions at presentation appeared as a globular noncystic mass attached to the back of the cornea, encroaching on the angle of the eye, and attached to the anterior surface of the iris at some points.Conclusion: SD-OCT for imaging the anterior segment allowed us to exclude the cystic nature of this pearly lesion. Some similarities may exist between these pearly lesions and superficial phlyctenular keratitis, which may support the immunological and inflammatory origin of these lesions.Keywords: pearl-like lesions, anterior chamber, phlycten, anterior segment OCTSoliman WWasfi EIAli OMDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 903-907 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Soliman W Wasfi EI Ali OM Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber
description	Wael Soliman, Ehab I Wasfi, Omar M AliDepartment of Ophthalmology, Assiut University Hospital, Assiut University, Assiut, Egypt*These authors contributed equally to this workAim: To study the morphological pattern of pearl-like lesions in the anterior chambers of children before and after management using anterior segment spectral domain optical coherence tomography (SD-OCT).Patients and methods: This was a prospective, observational cross-sectional study of patients presenting with peculiar pearl-like lesions in the anterior chamber of their eyes. 1 mL of betamethasone sodium phosphate (2 mg/mL) and betamethasone dipropionate (5 mg/mL) was injected subconjunctivally. Follow-ups of all patients were conducted for a period of 6 weeks. Anterior segment imaging was done using SD-OCT and also photo slit lamp before and after management.Results: Twelve eyes of 12 patients were included in this study. These patients presented with pearl-like lesions in the anterior chamber with signs of anterior uveitis. There was no history of ocular injury or tuberculosis in any patients. Six weeks after subconjunctival steroid injection, all patients achieved mean best-corrected visual acuity, which changed from 0.2 (range 0.1&ndash;0.4) to 0.5 (range 0.4&ndash;0.8), and the severity of iritis decreased. SD-OCT showed that the lesions at presentation appeared as a globular noncystic mass attached to the back of the cornea, encroaching on the angle of the eye, and attached to the anterior surface of the iris at some points.Conclusion: SD-OCT for imaging the anterior segment allowed us to exclude the cystic nature of this pearly lesion. Some similarities may exist between these pearly lesions and superficial phlyctenular keratitis, which may support the immunological and inflammatory origin of these lesions.Keywords: pearl-like lesions, anterior chamber, phlycten, anterior segment OCT
format	article
author	Soliman W Wasfi EI Ali OM
author_facet	Soliman W Wasfi EI Ali OM
author_sort	Soliman W
title	Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber
title_short	Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber
title_full	Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber
title_fullStr	Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber
title_full_unstemmed	Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber
title_sort	spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/df7ed69106f04616853e6a850c4c3499
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Spectral domain optical coherence tomography study of pearl-like lesions in the anterior chamber

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