Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.

<h4>Objective</h4>To validate the colposcopy indication proposed by the 2019 ASCCP Risk-Based Management Consensus Guidelines for abnormal cervical cancer screening tests (the 2019 ASCCP guidelines).<h4>Methods</h4>Clinical data of 1404 patients who underwent colposcopy in si...

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Autores principales:	Ting Gui, Zhiyan Chen, Fei Chen
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/df8831697a1a4078a5f0f46ca6d6ce3a
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spelling	oai:doaj.org-article:df8831697a1a4078a5f0f46ca6d6ce3a2021-12-02T20:09:49ZValidation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.1932-620310.1371/journal.pone.0253493https://doaj.org/article/df8831697a1a4078a5f0f46ca6d6ce3a2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253493https://doaj.org/toc/1932-6203<h4>Objective</h4>To validate the colposcopy indication proposed by the 2019 ASCCP Risk-Based Management Consensus Guidelines for abnormal cervical cancer screening tests (the 2019 ASCCP guidelines).<h4>Methods</h4>Clinical data of 1404 patients who underwent colposcopy in single center in China were reviewed. Based on history and current cervical screening (HPV & cytology), corresponding recommendations were given according to the 2019 ASCCP guidelines. The agreement and discrepancy of colposcopy indication were analyzed between the Chinese consensus and the 2019 ASCCP guidelines.<h4>Results</h4>Colposcopy indication was matched in about 80% patients. The left 20% were recommended with follow-up by the 2019 ASCCP guidelines. The discrepancy mainly focused on patients having a current result of HPV-positive NILM without unknown history. The ratio of observed CIN3+ in our database over estimated CIN3+ by the 2019 ASCCP guidelines was 6.2 (31/5). The ratio was even higher in patients with HPV16/18-positive NILM (7, 28/4), compared with those with other types of high-risk HPV-positive NILM (3, 3/1). The 2019 ASCCP guidelines had a relatively high sensitivity (83.1%), a low specificity (21.5%), a low positive predictive value (14.1%) and a high negative predictive value (89.1%) for prediction of CIN 3+.<h4>Conclusions</h4>We could try to apply the 2019 ASCCP guidelines in Chinese population. The classification of HR-HPV was strongly recommended during risk assessment. For patients with HPV16/18 infection, colposcopy should be recommended. Perspective multi-center randomized controlled trial with reliable follow-up should be performed in the future to confirm the feasibility.Ting GuiZhiyan ChenFei ChenPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 7, p e0253493 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ting Gui Zhiyan Chen Fei Chen Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.
description	<h4>Objective</h4>To validate the colposcopy indication proposed by the 2019 ASCCP Risk-Based Management Consensus Guidelines for abnormal cervical cancer screening tests (the 2019 ASCCP guidelines).<h4>Methods</h4>Clinical data of 1404 patients who underwent colposcopy in single center in China were reviewed. Based on history and current cervical screening (HPV & cytology), corresponding recommendations were given according to the 2019 ASCCP guidelines. The agreement and discrepancy of colposcopy indication were analyzed between the Chinese consensus and the 2019 ASCCP guidelines.<h4>Results</h4>Colposcopy indication was matched in about 80% patients. The left 20% were recommended with follow-up by the 2019 ASCCP guidelines. The discrepancy mainly focused on patients having a current result of HPV-positive NILM without unknown history. The ratio of observed CIN3+ in our database over estimated CIN3+ by the 2019 ASCCP guidelines was 6.2 (31/5). The ratio was even higher in patients with HPV16/18-positive NILM (7, 28/4), compared with those with other types of high-risk HPV-positive NILM (3, 3/1). The 2019 ASCCP guidelines had a relatively high sensitivity (83.1%), a low specificity (21.5%), a low positive predictive value (14.1%) and a high negative predictive value (89.1%) for prediction of CIN 3+.<h4>Conclusions</h4>We could try to apply the 2019 ASCCP guidelines in Chinese population. The classification of HR-HPV was strongly recommended during risk assessment. For patients with HPV16/18 infection, colposcopy should be recommended. Perspective multi-center randomized controlled trial with reliable follow-up should be performed in the future to confirm the feasibility.
format	article
author	Ting Gui Zhiyan Chen Fei Chen
author_facet	Ting Gui Zhiyan Chen Fei Chen
author_sort	Ting Gui
title	Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.
title_short	Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.
title_full	Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.
title_fullStr	Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.
title_full_unstemmed	Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.
title_sort	validation of the indication for colposcopy proposed by the 2019 asccp risk-based management consensus guidelines: a single-center study in china.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/df8831697a1a4078a5f0f46ca6d6ce3a
work_keys_str_mv	AT tinggui validationoftheindicationforcolposcopyproposedbythe2019asccpriskbasedmanagementconsensusguidelinesasinglecenterstudyinchina AT zhiyanchen validationoftheindicationforcolposcopyproposedbythe2019asccpriskbasedmanagementconsensusguidelinesasinglecenterstudyinchina AT feichen validationoftheindicationforcolposcopyproposedbythe2019asccpriskbasedmanagementconsensusguidelinesasinglecenterstudyinchina
_version_	1718375094281043968

Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China.

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