Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom

Here, using the diatom Phaeodactylum tricornutum as a model organism, the authors combine functional genomics, phylogenetics, and metabolic modeling to describe how diatoms might have functionally integrated nitrogen metabolism during evolution and how metabolic flux is regulated across cellular com...

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Autores principales: Sarah R. Smith, Chris L. Dupont, James K. McCarthy, Jared T. Broddrick, Miroslav Oborník, Aleš Horák, Zoltán Füssy, Jaromír Cihlář, Sabrina Kleessen, Hong Zheng, John P. McCrow, Kim K. Hixson, Wagner L. Araújo, Adriano Nunes-Nesi, Alisdair Fernie, Zoran Nikoloski, Bernhard O. Palsson, Andrew E. Allen
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/df8bdef394aa4d558203fcc3850cecce
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spelling oai:doaj.org-article:df8bdef394aa4d558203fcc3850cecce2021-12-02T16:57:41ZEvolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom10.1038/s41467-019-12407-y2041-1723https://doaj.org/article/df8bdef394aa4d558203fcc3850cecce2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12407-yhttps://doaj.org/toc/2041-1723Here, using the diatom Phaeodactylum tricornutum as a model organism, the authors combine functional genomics, phylogenetics, and metabolic modeling to describe how diatoms might have functionally integrated nitrogen metabolism during evolution and how metabolic flux is regulated across cellular compartmentsSarah R. SmithChris L. DupontJames K. McCarthyJared T. BroddrickMiroslav OborníkAleš HorákZoltán FüssyJaromír CihlářSabrina KleessenHong ZhengJohn P. McCrowKim K. HixsonWagner L. AraújoAdriano Nunes-NesiAlisdair FernieZoran NikoloskiBernhard O. PalssonAndrew E. AllenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sarah R. Smith
Chris L. Dupont
James K. McCarthy
Jared T. Broddrick
Miroslav Oborník
Aleš Horák
Zoltán Füssy
Jaromír Cihlář
Sabrina Kleessen
Hong Zheng
John P. McCrow
Kim K. Hixson
Wagner L. Araújo
Adriano Nunes-Nesi
Alisdair Fernie
Zoran Nikoloski
Bernhard O. Palsson
Andrew E. Allen
Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom
description Here, using the diatom Phaeodactylum tricornutum as a model organism, the authors combine functional genomics, phylogenetics, and metabolic modeling to describe how diatoms might have functionally integrated nitrogen metabolism during evolution and how metabolic flux is regulated across cellular compartments
format article
author Sarah R. Smith
Chris L. Dupont
James K. McCarthy
Jared T. Broddrick
Miroslav Oborník
Aleš Horák
Zoltán Füssy
Jaromír Cihlář
Sabrina Kleessen
Hong Zheng
John P. McCrow
Kim K. Hixson
Wagner L. Araújo
Adriano Nunes-Nesi
Alisdair Fernie
Zoran Nikoloski
Bernhard O. Palsson
Andrew E. Allen
author_facet Sarah R. Smith
Chris L. Dupont
James K. McCarthy
Jared T. Broddrick
Miroslav Oborník
Aleš Horák
Zoltán Füssy
Jaromír Cihlář
Sabrina Kleessen
Hong Zheng
John P. McCrow
Kim K. Hixson
Wagner L. Araújo
Adriano Nunes-Nesi
Alisdair Fernie
Zoran Nikoloski
Bernhard O. Palsson
Andrew E. Allen
author_sort Sarah R. Smith
title Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom
title_short Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom
title_full Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom
title_fullStr Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom
title_full_unstemmed Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom
title_sort evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/df8bdef394aa4d558203fcc3850cecce
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