Dynamic changes in epithelial cell morphology control thymic organ size during atrophy and regeneration

One aspect of ageing on immunity is attributed to accelerated thymic atrophy, but the underlying mechanism is still lacking. Here the authors show, using conditional reporter mouse models, that both atrophy and regeneration of the thymus are regulated by rate-limiting morphological changes in epithe...

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Bibliographic Details
Main Authors: Thomas Venables, Ann V. Griffith, Alice DeAraujo, Howard T. Petrie
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/df914271f29b44e993752f1172f879f4
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