Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming
The mechanisms that restore endothelial barrier integrity following inflammation-induced breaching are incompletely understood. Here the authors show that the CD31 immune receptor contributes to reestablishing vascular integrity via its effects on endothelial cell metabolism.
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Nature Portfolio
2020
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oai:doaj.org-article:df928ac93a0a4597a8951f70e8733d1b2021-12-02T18:37:05ZPreservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming10.1038/s41467-020-17329-82041-1723https://doaj.org/article/df928ac93a0a4597a8951f70e8733d1b2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17329-8https://doaj.org/toc/2041-1723The mechanisms that restore endothelial barrier integrity following inflammation-induced breaching are incompletely understood. Here the authors show that the CD31 immune receptor contributes to reestablishing vascular integrity via its effects on endothelial cell metabolism.Kenneth C. P. CheungSilvia FantiClaudio MauroGuosu WangAnitha S. NairHongmei FuSilvia AngelettiSilvia SpotoMarta FogolariFrancesco RomanoDunja AksentijevicWeiwei LiuBaiying LiLixin ChengLiwen JiangJuho VuononvirtaThanushiyan R. PoobalasingamDavid M. SmithMassimo CiccozziEgle SolitoFederica M. Marelli-BergNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
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EN |
topic |
Science Q |
spellingShingle |
Science Q Kenneth C. P. Cheung Silvia Fanti Claudio Mauro Guosu Wang Anitha S. Nair Hongmei Fu Silvia Angeletti Silvia Spoto Marta Fogolari Francesco Romano Dunja Aksentijevic Weiwei Liu Baiying Li Lixin Cheng Liwen Jiang Juho Vuononvirta Thanushiyan R. Poobalasingam David M. Smith Massimo Ciccozzi Egle Solito Federica M. Marelli-Berg Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming |
description |
The mechanisms that restore endothelial barrier integrity following inflammation-induced breaching are incompletely understood. Here the authors show that the CD31 immune receptor contributes to reestablishing vascular integrity via its effects on endothelial cell metabolism. |
format |
article |
author |
Kenneth C. P. Cheung Silvia Fanti Claudio Mauro Guosu Wang Anitha S. Nair Hongmei Fu Silvia Angeletti Silvia Spoto Marta Fogolari Francesco Romano Dunja Aksentijevic Weiwei Liu Baiying Li Lixin Cheng Liwen Jiang Juho Vuononvirta Thanushiyan R. Poobalasingam David M. Smith Massimo Ciccozzi Egle Solito Federica M. Marelli-Berg |
author_facet |
Kenneth C. P. Cheung Silvia Fanti Claudio Mauro Guosu Wang Anitha S. Nair Hongmei Fu Silvia Angeletti Silvia Spoto Marta Fogolari Francesco Romano Dunja Aksentijevic Weiwei Liu Baiying Li Lixin Cheng Liwen Jiang Juho Vuononvirta Thanushiyan R. Poobalasingam David M. Smith Massimo Ciccozzi Egle Solito Federica M. Marelli-Berg |
author_sort |
Kenneth C. P. Cheung |
title |
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming |
title_short |
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming |
title_full |
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming |
title_fullStr |
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming |
title_full_unstemmed |
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming |
title_sort |
preservation of microvascular barrier function requires cd31 receptor-induced metabolic reprogramming |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/df928ac93a0a4597a8951f70e8733d1b |
work_keys_str_mv |
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