Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vic...
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Nature Portfolio
2018
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oai:doaj.org-article:dfa1646e7c8f40d28dd85fc0c17607662021-12-02T14:39:06ZDual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols10.1038/s41467-017-02698-42041-1723https://doaj.org/article/dfa1646e7c8f40d28dd85fc0c17607662018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02698-4https://doaj.org/toc/2041-1723Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vicinal amino alcohols.Chen-Xi YeYared Yohannes MelcamuHeng-Hui LiJiang-Tao ChengTian-Tian ZhangYuan-Ping RuanXiao ZhengXin LuPei-Qiang HuangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Chen-Xi Ye Yared Yohannes Melcamu Heng-Hui Li Jiang-Tao Cheng Tian-Tian Zhang Yuan-Ping Ruan Xiao Zheng Xin Lu Pei-Qiang Huang Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols |
description |
Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vicinal amino alcohols. |
format |
article |
author |
Chen-Xi Ye Yared Yohannes Melcamu Heng-Hui Li Jiang-Tao Cheng Tian-Tian Zhang Yuan-Ping Ruan Xiao Zheng Xin Lu Pei-Qiang Huang |
author_facet |
Chen-Xi Ye Yared Yohannes Melcamu Heng-Hui Li Jiang-Tao Cheng Tian-Tian Zhang Yuan-Ping Ruan Xiao Zheng Xin Lu Pei-Qiang Huang |
author_sort |
Chen-Xi Ye |
title |
Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols |
title_short |
Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols |
title_full |
Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols |
title_fullStr |
Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols |
title_full_unstemmed |
Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols |
title_sort |
dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/dfa1646e7c8f40d28dd85fc0c1760766 |
work_keys_str_mv |
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1718390743366631424 |