Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols

Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vic...

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Autores principales: Chen-Xi Ye, Yared Yohannes Melcamu, Heng-Hui Li, Jiang-Tao Cheng, Tian-Tian Zhang, Yuan-Ping Ruan, Xiao Zheng, Xin Lu, Pei-Qiang Huang
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Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/dfa1646e7c8f40d28dd85fc0c1760766
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spelling oai:doaj.org-article:dfa1646e7c8f40d28dd85fc0c17607662021-12-02T14:39:06ZDual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols10.1038/s41467-017-02698-42041-1723https://doaj.org/article/dfa1646e7c8f40d28dd85fc0c17607662018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02698-4https://doaj.org/toc/2041-1723Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vicinal amino alcohols.Chen-Xi YeYared Yohannes MelcamuHeng-Hui LiJiang-Tao ChengTian-Tian ZhangYuan-Ping RuanXiao ZhengXin LuPei-Qiang HuangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chen-Xi Ye
Yared Yohannes Melcamu
Heng-Hui Li
Jiang-Tao Cheng
Tian-Tian Zhang
Yuan-Ping Ruan
Xiao Zheng
Xin Lu
Pei-Qiang Huang
Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
description Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vicinal amino alcohols.
format article
author Chen-Xi Ye
Yared Yohannes Melcamu
Heng-Hui Li
Jiang-Tao Cheng
Tian-Tian Zhang
Yuan-Ping Ruan
Xiao Zheng
Xin Lu
Pei-Qiang Huang
author_facet Chen-Xi Ye
Yared Yohannes Melcamu
Heng-Hui Li
Jiang-Tao Cheng
Tian-Tian Zhang
Yuan-Ping Ruan
Xiao Zheng
Xin Lu
Pei-Qiang Huang
author_sort Chen-Xi Ye
title Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_short Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_full Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_fullStr Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_full_unstemmed Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_sort dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/dfa1646e7c8f40d28dd85fc0c1760766
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AT henghuili dualcatalysisforenantioselectiveconvergentsynthesisofenantiopurevicinalaminoalcohols
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