Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols

Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vic...

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Main Authors:	Chen-Xi Ye, Yared Yohannes Melcamu, Heng-Hui Li, Jiang-Tao Cheng, Tian-Tian Zhang, Yuan-Ping Ruan, Xiao Zheng, Xin Lu, Pei-Qiang Huang
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/dfa1646e7c8f40d28dd85fc0c1760766
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spelling	oai:doaj.org-article:dfa1646e7c8f40d28dd85fc0c17607662021-12-02T14:39:06ZDual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols10.1038/s41467-017-02698-42041-1723https://doaj.org/article/dfa1646e7c8f40d28dd85fc0c17607662018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02698-4https://doaj.org/toc/2041-1723Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vicinal amino alcohols.Chen-Xi YeYared Yohannes MelcamuHeng-Hui LiJiang-Tao ChengTian-Tian ZhangYuan-Ping RuanXiao ZhengXin LuPei-Qiang HuangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chen-Xi Ye Yared Yohannes Melcamu Heng-Hui Li Jiang-Tao Cheng Tian-Tian Zhang Yuan-Ping Ruan Xiao Zheng Xin Lu Pei-Qiang Huang Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
description	Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vicinal amino alcohols.
format	article
author	Chen-Xi Ye Yared Yohannes Melcamu Heng-Hui Li Jiang-Tao Cheng Tian-Tian Zhang Yuan-Ping Ruan Xiao Zheng Xin Lu Pei-Qiang Huang
author_facet	Chen-Xi Ye Yared Yohannes Melcamu Heng-Hui Li Jiang-Tao Cheng Tian-Tian Zhang Yuan-Ping Ruan Xiao Zheng Xin Lu Pei-Qiang Huang
author_sort	Chen-Xi Ye
title	Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_short	Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_full	Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_fullStr	Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_full_unstemmed	Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
title_sort	dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/dfa1646e7c8f40d28dd85fc0c1760766
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Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols

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