Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence

Roberta Piva,1 Flavia Ticconi,1 Valentina Ceriani,1 Federica Scalorbi,2 Francesco Fiz,1 Selene Capitanio,3 Matteo Bauckneht,1 Giuseppe Cittadini,4 Gianmario Sambuceti,1 Silvia Morbelli5 1Nuclear Medicine Unit, Department of Health Sciences, University of Genoa, Genoa, 2Nuclear Medicine Unit, S. Orso...

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Autores principales: Piva R, Ticconi F, Ceriani V, Scalorbi F, Fiz F, Capitanio S, Bauckneht M, Cittadini G, Sambuceti G, Morbelli S
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Lenguaje:EN
Publicado: Dove Medical Press 2017
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Acceso en línea:https://doaj.org/article/dfaed65fd2884eb696627f27729d6f0c
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spelling oai:doaj.org-article:dfaed65fd2884eb696627f27729d6f0c2021-12-02T07:18:58ZComparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence1179-1314https://doaj.org/article/dfaed65fd2884eb696627f27729d6f0c2017-07-01T00:00:00Zhttps://www.dovepress.com/comparative-diagnostic-accuracy-of-18f-fdg-petct-for-breast-cancer-rec-peer-reviewed-article-BCTThttps://doaj.org/toc/1179-1314Roberta Piva,1 Flavia Ticconi,1 Valentina Ceriani,1 Federica Scalorbi,2 Francesco Fiz,1 Selene Capitanio,3 Matteo Bauckneht,1 Giuseppe Cittadini,4 Gianmario Sambuceti,1 Silvia Morbelli5 1Nuclear Medicine Unit, Department of Health Sciences, University of Genoa, Genoa, 2Nuclear Medicine Unit, S. Orsola-Malpighi University Hospital, Bologna, 3Nuclear Medicine Unit, ASUITS, Trieste, 4Department of Radiology, IRCCS AOU San Martino – IST, 5Nuclear Medicine Unit, IRCCS AOU San Martino – IST, Genoa, Italy Abstract: In the last decades, in addition to conventional imaging techniques and magnetic resonance imaging (MRI), 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has been shown to be relevant in the detection and management of breast cancer recurrence in doubtful cases in selected groups of patients. While there are no conclusive data indicating that imaging tests, including FDG PET/CT, produce a survival benefit in asymptomatic patients, FDG PET/CT can be useful for identifying the site of relapse when traditional imaging methods are equivocal or conflicting and for identifying or confirming isolated loco-regional relapse or isolated metastatic lesions. The present narrative review deals with the potential role of FDG PET in these clinical settings by comparing its accuracy and impact with conventional imaging modalities such as CT, ultrasound, bone scan, 18F-sodium fluoride PET/CT (18F-NaF PET/CT) as well as MRI. Patient-focused perspectives in terms of patients’ satisfaction and acceptability are also discussed. Keywords: breast cancer, positron emission tomography, restagingPiva RTicconi FCeriani VScalorbi FFiz FCapitanio SBauckneht MCittadini GSambuceti GMorbelli SDove Medical Pressarticlebreast cancerpositron emission tomographyrestaging.Neoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol Volume 9, Pp 461-471 (2017)
institution DOAJ
collection DOAJ
language EN
topic breast cancer
positron emission tomography
restaging.
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle breast cancer
positron emission tomography
restaging.
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Piva R
Ticconi F
Ceriani V
Scalorbi F
Fiz F
Capitanio S
Bauckneht M
Cittadini G
Sambuceti G
Morbelli S
Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence
description Roberta Piva,1 Flavia Ticconi,1 Valentina Ceriani,1 Federica Scalorbi,2 Francesco Fiz,1 Selene Capitanio,3 Matteo Bauckneht,1 Giuseppe Cittadini,4 Gianmario Sambuceti,1 Silvia Morbelli5 1Nuclear Medicine Unit, Department of Health Sciences, University of Genoa, Genoa, 2Nuclear Medicine Unit, S. Orsola-Malpighi University Hospital, Bologna, 3Nuclear Medicine Unit, ASUITS, Trieste, 4Department of Radiology, IRCCS AOU San Martino – IST, 5Nuclear Medicine Unit, IRCCS AOU San Martino – IST, Genoa, Italy Abstract: In the last decades, in addition to conventional imaging techniques and magnetic resonance imaging (MRI), 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has been shown to be relevant in the detection and management of breast cancer recurrence in doubtful cases in selected groups of patients. While there are no conclusive data indicating that imaging tests, including FDG PET/CT, produce a survival benefit in asymptomatic patients, FDG PET/CT can be useful for identifying the site of relapse when traditional imaging methods are equivocal or conflicting and for identifying or confirming isolated loco-regional relapse or isolated metastatic lesions. The present narrative review deals with the potential role of FDG PET in these clinical settings by comparing its accuracy and impact with conventional imaging modalities such as CT, ultrasound, bone scan, 18F-sodium fluoride PET/CT (18F-NaF PET/CT) as well as MRI. Patient-focused perspectives in terms of patients’ satisfaction and acceptability are also discussed. Keywords: breast cancer, positron emission tomography, restaging
format article
author Piva R
Ticconi F
Ceriani V
Scalorbi F
Fiz F
Capitanio S
Bauckneht M
Cittadini G
Sambuceti G
Morbelli S
author_facet Piva R
Ticconi F
Ceriani V
Scalorbi F
Fiz F
Capitanio S
Bauckneht M
Cittadini G
Sambuceti G
Morbelli S
author_sort Piva R
title Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence
title_short Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence
title_full Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence
title_fullStr Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence
title_full_unstemmed Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence
title_sort comparative diagnostic accuracy of 18f-fdg pet/ct for breast cancer recurrence
publisher Dove Medical Press
publishDate 2017
url https://doaj.org/article/dfaed65fd2884eb696627f27729d6f0c
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