Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence
Roberta Piva,1 Flavia Ticconi,1 Valentina Ceriani,1 Federica Scalorbi,2 Francesco Fiz,1 Selene Capitanio,3 Matteo Bauckneht,1 Giuseppe Cittadini,4 Gianmario Sambuceti,1 Silvia Morbelli5 1Nuclear Medicine Unit, Department of Health Sciences, University of Genoa, Genoa, 2Nuclear Medicine Unit, S. Orso...
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Dove Medical Press
2017
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oai:doaj.org-article:dfaed65fd2884eb696627f27729d6f0c2021-12-02T07:18:58ZComparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence1179-1314https://doaj.org/article/dfaed65fd2884eb696627f27729d6f0c2017-07-01T00:00:00Zhttps://www.dovepress.com/comparative-diagnostic-accuracy-of-18f-fdg-petct-for-breast-cancer-rec-peer-reviewed-article-BCTThttps://doaj.org/toc/1179-1314Roberta Piva,1 Flavia Ticconi,1 Valentina Ceriani,1 Federica Scalorbi,2 Francesco Fiz,1 Selene Capitanio,3 Matteo Bauckneht,1 Giuseppe Cittadini,4 Gianmario Sambuceti,1 Silvia Morbelli5 1Nuclear Medicine Unit, Department of Health Sciences, University of Genoa, Genoa, 2Nuclear Medicine Unit, S. Orsola-Malpighi University Hospital, Bologna, 3Nuclear Medicine Unit, ASUITS, Trieste, 4Department of Radiology, IRCCS AOU San Martino – IST, 5Nuclear Medicine Unit, IRCCS AOU San Martino – IST, Genoa, Italy Abstract: In the last decades, in addition to conventional imaging techniques and magnetic resonance imaging (MRI), 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has been shown to be relevant in the detection and management of breast cancer recurrence in doubtful cases in selected groups of patients. While there are no conclusive data indicating that imaging tests, including FDG PET/CT, produce a survival benefit in asymptomatic patients, FDG PET/CT can be useful for identifying the site of relapse when traditional imaging methods are equivocal or conflicting and for identifying or confirming isolated loco-regional relapse or isolated metastatic lesions. The present narrative review deals with the potential role of FDG PET in these clinical settings by comparing its accuracy and impact with conventional imaging modalities such as CT, ultrasound, bone scan, 18F-sodium fluoride PET/CT (18F-NaF PET/CT) as well as MRI. Patient-focused perspectives in terms of patients’ satisfaction and acceptability are also discussed. Keywords: breast cancer, positron emission tomography, restagingPiva RTicconi FCeriani VScalorbi FFiz FCapitanio SBauckneht MCittadini GSambuceti GMorbelli SDove Medical Pressarticlebreast cancerpositron emission tomographyrestaging.Neoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol Volume 9, Pp 461-471 (2017) |
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breast cancer positron emission tomography restaging. Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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breast cancer positron emission tomography restaging. Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Piva R Ticconi F Ceriani V Scalorbi F Fiz F Capitanio S Bauckneht M Cittadini G Sambuceti G Morbelli S Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence |
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Roberta Piva,1 Flavia Ticconi,1 Valentina Ceriani,1 Federica Scalorbi,2 Francesco Fiz,1 Selene Capitanio,3 Matteo Bauckneht,1 Giuseppe Cittadini,4 Gianmario Sambuceti,1 Silvia Morbelli5 1Nuclear Medicine Unit, Department of Health Sciences, University of Genoa, Genoa, 2Nuclear Medicine Unit, S. Orsola-Malpighi University Hospital, Bologna, 3Nuclear Medicine Unit, ASUITS, Trieste, 4Department of Radiology, IRCCS AOU San Martino – IST, 5Nuclear Medicine Unit, IRCCS AOU San Martino – IST, Genoa, Italy Abstract: In the last decades, in addition to conventional imaging techniques and magnetic resonance imaging (MRI), 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has been shown to be relevant in the detection and management of breast cancer recurrence in doubtful cases in selected groups of patients. While there are no conclusive data indicating that imaging tests, including FDG PET/CT, produce a survival benefit in asymptomatic patients, FDG PET/CT can be useful for identifying the site of relapse when traditional imaging methods are equivocal or conflicting and for identifying or confirming isolated loco-regional relapse or isolated metastatic lesions. The present narrative review deals with the potential role of FDG PET in these clinical settings by comparing its accuracy and impact with conventional imaging modalities such as CT, ultrasound, bone scan, 18F-sodium fluoride PET/CT (18F-NaF PET/CT) as well as MRI. Patient-focused perspectives in terms of patients’ satisfaction and acceptability are also discussed. Keywords: breast cancer, positron emission tomography, restaging |
format |
article |
author |
Piva R Ticconi F Ceriani V Scalorbi F Fiz F Capitanio S Bauckneht M Cittadini G Sambuceti G Morbelli S |
author_facet |
Piva R Ticconi F Ceriani V Scalorbi F Fiz F Capitanio S Bauckneht M Cittadini G Sambuceti G Morbelli S |
author_sort |
Piva R |
title |
Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence |
title_short |
Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence |
title_full |
Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence |
title_fullStr |
Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence |
title_full_unstemmed |
Comparative diagnostic accuracy of 18F-FDG PET/CT for breast cancer recurrence |
title_sort |
comparative diagnostic accuracy of 18f-fdg pet/ct for breast cancer recurrence |
publisher |
Dove Medical Press |
publishDate |
2017 |
url |
https://doaj.org/article/dfaed65fd2884eb696627f27729d6f0c |
work_keys_str_mv |
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