MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY

Ultrastructural changes of renal and hepatic mitochondria in mice induced by OA were studied. Mitrochondria exhibited diverse morphological aberrations. The outer mitochondria) membranes, cristae and matrix were affected. The changes were more prominent in the proximal and distal convoluted tubule...

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Autores principales:	N. Divakaran Nair, M. Krishnan Nair, Koshy Varghese, T. Sreekumaran
Formato:	article
Lenguaje:	EN
Publicado:	Director of Academics and Research, Kerala Veterinary and Animal Sciences University 1994
Materias:	Animal biochemistry QP501-801 Science (General) Q1-390
Acceso en línea:	https://doaj.org/article/dfc5ed02c08d4f5a8491f236795e3a71
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spelling	oai:doaj.org-article:dfc5ed02c08d4f5a8491f236795e3a712021-11-12T14:08:13ZMITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY0971-07012582-0605https://doaj.org/article/dfc5ed02c08d4f5a8491f236795e3a711994-01-01T00:00:00Zhttps://www.jvas.in/public_html/upload/article_file/article_file_r2b12l.pdf?t=r2b12phttps://doaj.org/toc/0971-0701https://doaj.org/toc/2582-0605Ultrastructural changes of renal and hepatic mitochondria in mice induced by OA were studied. Mitrochondria exhibited diverse morphological aberrations. The outer mitochondria) membranes, cristae and matrix were affected. The changes were more prominent in the proximal and distal convoluted tubules of kidney. In the liver, besides the mitochondrial changes, there was proliferation of SER. An increase in the peroxisomes was observed in the kidney and liver. The morphological aberrations seen in die mitochondria indicate that OA has a direct toxic action on the mitochondria causing aberrations of mitochondrial fuction resultnig in metabolic derangement in the cell. N. Divakaran NairM. Krishnan NairKoshy VargheseT. SreekumaranDirector of Academics and Research, Kerala Veterinary and Animal Sciences UniversityarticleAnimal biochemistryQP501-801Science (General)Q1-390ENJournal of Veterinary and Animal Sciences, Vol 25, Iss 1, Pp 25-32 (1994)
institution	DOAJ
collection	DOAJ
language	EN
topic	Animal biochemistry QP501-801 Science (General) Q1-390
spellingShingle	Animal biochemistry QP501-801 Science (General) Q1-390 N. Divakaran Nair M. Krishnan Nair Koshy Varghese T. Sreekumaran MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY
description	Ultrastructural changes of renal and hepatic mitochondria in mice induced by OA were studied. Mitrochondria exhibited diverse morphological aberrations. The outer mitochondria) membranes, cristae and matrix were affected. The changes were more prominent in the proximal and distal convoluted tubules of kidney. In the liver, besides the mitochondrial changes, there was proliferation of SER. An increase in the peroxisomes was observed in the kidney and liver. The morphological aberrations seen in die mitochondria indicate that OA has a direct toxic action on the mitochondria causing aberrations of mitochondrial fuction resultnig in metabolic derangement in the cell.
format	article
author	N. Divakaran Nair M. Krishnan Nair Koshy Varghese T. Sreekumaran
author_facet	N. Divakaran Nair M. Krishnan Nair Koshy Varghese T. Sreekumaran
author_sort	N. Divakaran Nair
title	MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY
title_short	MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY
title_full	MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY
title_fullStr	MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY
title_full_unstemmed	MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY
title_sort	mitochondrial changes in the kidney and liver ot mice induced by ochratoxin a - an electronmicroscopic study
publisher	Director of Academics and Research, Kerala Veterinary and Animal Sciences University
publishDate	1994
url	https://doaj.org/article/dfc5ed02c08d4f5a8491f236795e3a71
work_keys_str_mv	AT ndivakarannair mitochondrialchangesinthekidneyandliverotmiceinducedbyochratoxinaanelectronmicroscopicstudy AT mkrishnannair mitochondrialchangesinthekidneyandliverotmiceinducedbyochratoxinaanelectronmicroscopicstudy AT koshyvarghese mitochondrialchangesinthekidneyandliverotmiceinducedbyochratoxinaanelectronmicroscopicstudy AT tsreekumaran mitochondrialchangesinthekidneyandliverotmiceinducedbyochratoxinaanelectronmicroscopicstudy
_version_	1718430403232006144

MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY

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