Circadian control of lung inflammation in influenza infection

The circadian clock affects immune responses, but its role in influenza infection is not well understood. Here, Sengupta et al. show that time of infection and the circadian clock have no effect on lung virus titers, but affect inflammation, morbidity and mortality.

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Autores principales: Shaon Sengupta, Soon Y. Tang, Jill C. Devine, Seán T. Anderson, Soumyashant Nayak, Shirley L. Zhang, Alex Valenzuela, Devin G. Fisher, Gregory R. Grant, Carolina B. López, Garret A. FitzGerald
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/dfd0fc631a7044e1aeeb24d20b853a8f
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spelling oai:doaj.org-article:dfd0fc631a7044e1aeeb24d20b853a8f2021-12-02T14:38:45ZCircadian control of lung inflammation in influenza infection10.1038/s41467-019-11400-92041-1723https://doaj.org/article/dfd0fc631a7044e1aeeb24d20b853a8f2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11400-9https://doaj.org/toc/2041-1723The circadian clock affects immune responses, but its role in influenza infection is not well understood. Here, Sengupta et al. show that time of infection and the circadian clock have no effect on lung virus titers, but affect inflammation, morbidity and mortality.Shaon SenguptaSoon Y. TangJill C. DevineSeán T. AndersonSoumyashant NayakShirley L. ZhangAlex ValenzuelaDevin G. FisherGregory R. GrantCarolina B. LópezGarret A. FitzGeraldNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shaon Sengupta
Soon Y. Tang
Jill C. Devine
Seán T. Anderson
Soumyashant Nayak
Shirley L. Zhang
Alex Valenzuela
Devin G. Fisher
Gregory R. Grant
Carolina B. López
Garret A. FitzGerald
Circadian control of lung inflammation in influenza infection
description The circadian clock affects immune responses, but its role in influenza infection is not well understood. Here, Sengupta et al. show that time of infection and the circadian clock have no effect on lung virus titers, but affect inflammation, morbidity and mortality.
format article
author Shaon Sengupta
Soon Y. Tang
Jill C. Devine
Seán T. Anderson
Soumyashant Nayak
Shirley L. Zhang
Alex Valenzuela
Devin G. Fisher
Gregory R. Grant
Carolina B. López
Garret A. FitzGerald
author_facet Shaon Sengupta
Soon Y. Tang
Jill C. Devine
Seán T. Anderson
Soumyashant Nayak
Shirley L. Zhang
Alex Valenzuela
Devin G. Fisher
Gregory R. Grant
Carolina B. López
Garret A. FitzGerald
author_sort Shaon Sengupta
title Circadian control of lung inflammation in influenza infection
title_short Circadian control of lung inflammation in influenza infection
title_full Circadian control of lung inflammation in influenza infection
title_fullStr Circadian control of lung inflammation in influenza infection
title_full_unstemmed Circadian control of lung inflammation in influenza infection
title_sort circadian control of lung inflammation in influenza infection
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/dfd0fc631a7044e1aeeb24d20b853a8f
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AT jillcdevine circadiancontroloflunginflammationininfluenzainfection
AT seantanderson circadiancontroloflunginflammationininfluenzainfection
AT soumyashantnayak circadiancontroloflunginflammationininfluenzainfection
AT shirleylzhang circadiancontroloflunginflammationininfluenzainfection
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