Circadian control of lung inflammation in influenza infection

The circadian clock affects immune responses, but its role in influenza infection is not well understood. Here, Sengupta et al. show that time of infection and the circadian clock have no effect on lung virus titers, but affect inflammation, morbidity and mortality.

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Bibliographic Details
Main Authors:	Shaon Sengupta, Soon Y. Tang, Jill C. Devine, Seán T. Anderson, Soumyashant Nayak, Shirley L. Zhang, Alex Valenzuela, Devin G. Fisher, Gregory R. Grant, Carolina B. López, Garret A. FitzGerald
Format:	article
Language:	EN
Published:	Nature Portfolio 2019
Subjects:	Science Q
Online Access:	https://doaj.org/article/dfd0fc631a7044e1aeeb24d20b853a8f
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spelling	oai:doaj.org-article:dfd0fc631a7044e1aeeb24d20b853a8f2021-12-02T14:38:45ZCircadian control of lung inflammation in influenza infection10.1038/s41467-019-11400-92041-1723https://doaj.org/article/dfd0fc631a7044e1aeeb24d20b853a8f2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11400-9https://doaj.org/toc/2041-1723The circadian clock affects immune responses, but its role in influenza infection is not well understood. Here, Sengupta et al. show that time of infection and the circadian clock have no effect on lung virus titers, but affect inflammation, morbidity and mortality.Shaon SenguptaSoon Y. TangJill C. DevineSeán T. AndersonSoumyashant NayakShirley L. ZhangAlex ValenzuelaDevin G. FisherGregory R. GrantCarolina B. LópezGarret A. FitzGeraldNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shaon Sengupta Soon Y. Tang Jill C. Devine Seán T. Anderson Soumyashant Nayak Shirley L. Zhang Alex Valenzuela Devin G. Fisher Gregory R. Grant Carolina B. López Garret A. FitzGerald Circadian control of lung inflammation in influenza infection
description	The circadian clock affects immune responses, but its role in influenza infection is not well understood. Here, Sengupta et al. show that time of infection and the circadian clock have no effect on lung virus titers, but affect inflammation, morbidity and mortality.
format	article
author	Shaon Sengupta Soon Y. Tang Jill C. Devine Seán T. Anderson Soumyashant Nayak Shirley L. Zhang Alex Valenzuela Devin G. Fisher Gregory R. Grant Carolina B. López Garret A. FitzGerald
author_facet	Shaon Sengupta Soon Y. Tang Jill C. Devine Seán T. Anderson Soumyashant Nayak Shirley L. Zhang Alex Valenzuela Devin G. Fisher Gregory R. Grant Carolina B. López Garret A. FitzGerald
author_sort	Shaon Sengupta
title	Circadian control of lung inflammation in influenza infection
title_short	Circadian control of lung inflammation in influenza infection
title_full	Circadian control of lung inflammation in influenza infection
title_fullStr	Circadian control of lung inflammation in influenza infection
title_full_unstemmed	Circadian control of lung inflammation in influenza infection
title_sort	circadian control of lung inflammation in influenza infection
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/dfd0fc631a7044e1aeeb24d20b853a8f
work_keys_str_mv	AT shaonsengupta circadiancontroloflunginflammationininfluenzainfection AT soonytang circadiancontroloflunginflammationininfluenzainfection AT jillcdevine circadiancontroloflunginflammationininfluenzainfection AT seantanderson circadiancontroloflunginflammationininfluenzainfection AT soumyashantnayak circadiancontroloflunginflammationininfluenzainfection AT shirleylzhang circadiancontroloflunginflammationininfluenzainfection AT alexvalenzuela circadiancontroloflunginflammationininfluenzainfection AT devingfisher circadiancontroloflunginflammationininfluenzainfection AT gregoryrgrant circadiancontroloflunginflammationininfluenzainfection AT carolinablopez circadiancontroloflunginflammationininfluenzainfection AT garretafitzgerald circadiancontroloflunginflammationininfluenzainfection
_version_	1718390925004111872

Circadian control of lung inflammation in influenza infection

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