Constructing germline research cohorts from the discarded reads of clinical tumor sequences
Abstract Background Hundreds of thousands of cancer patients have had targeted (panel) tumor sequencing to identify clinically meaningful mutations. In addition to improving patient outcomes, this activity has led to significant discoveries in basic and translational domains. However, the targeted n...
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Main Authors: | Alexander Gusev, Stefan Groha, Kodi Taraszka, Yevgeniy R. Semenov, Noah Zaitlen |
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Format: | article |
Language: | EN |
Published: |
BMC
2021
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Online Access: | https://doaj.org/article/dfd1ed628f8e4314b50a12954fd90ff0 |
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