Constructing germline research cohorts from the discarded reads of clinical tumor sequences
Abstract Background Hundreds of thousands of cancer patients have had targeted (panel) tumor sequencing to identify clinically meaningful mutations. In addition to improving patient outcomes, this activity has led to significant discoveries in basic and translational domains. However, the targeted n...
Enregistré dans:
Auteurs principaux: | Alexander Gusev, Stefan Groha, Kodi Taraszka, Yevgeniy R. Semenov, Noah Zaitlen |
---|---|
Format: | article |
Langue: | EN |
Publié: |
BMC
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/dfd1ed628f8e4314b50a12954fd90ff0 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Identifying causal variants by fine mapping across multiple studies.
par: Nathan LaPierre, et autres
Publié: (2021) -
Longitudinal and multi-tissue molecular diagnostics track somatic BRCA2 reversion mutations that correct the open reading frame of germline alteration upon clinical relapse
par: Shelly Sorrells, et autres
Publié: (2021) -
Germline genome modification through novel political, ethical, and social lenses.
par: Vicki Xafis, et autres
Publié: (2021) -
Germline genome editing: Moratorium, hard law, or an informed adaptive consensus?
par: Terry Kaan, et autres
Publié: (2021) -
dRTEL1 is essential for the maintenance of Drosophila male germline stem cells.
par: Ying Yang, et autres
Publié: (2021)