Evolution of Bacterial “Frenemies”

ABSTRACT Chronic polymicrobial infections are associated with increased virulence compared to monospecies infections. However, our understanding of microbial dynamics during polymicrobial infection is limited. A recent study by Limoli and colleagues (D. H. Limoli, G. B. Whitfield, T. Kitao, M. L. Iv...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sophie E. Darch, Carolyn B. Ibberson, Marvin Whiteley
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2017
Materias:	Pseudomonas aeruginosa Staphylococcus aureus aggregates biofilms coinfection cystic fibrosis Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/dfd633706751468a949d0afcc7d7515b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:dfd633706751468a949d0afcc7d7515b
record_format	dspace
spelling	oai:doaj.org-article:dfd633706751468a949d0afcc7d7515b2021-11-15T15:51:31ZEvolution of Bacterial “Frenemies”10.1128/mBio.00675-172150-7511https://doaj.org/article/dfd633706751468a949d0afcc7d7515b2017-07-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00675-17https://doaj.org/toc/2150-7511ABSTRACT Chronic polymicrobial infections are associated with increased virulence compared to monospecies infections. However, our understanding of microbial dynamics during polymicrobial infection is limited. A recent study by Limoli and colleagues (D. H. Limoli, G. B. Whitfield, T. Kitao, M. L. Ivey, M. R. Davis, Jr., et al., mBio 8:e00186-17, 2017, https://doi.org/10.1128/mBio.00186-17 ) provides insight into a mechanism that may contribute to the coexistence of Pseudomonas aeruginosa and Staphylococcus aureus in the cystic fibrosis (CF) lung. CF lung infections have frequently been used to investigate microbial interactions due to both the complex polymicrobial community and chronic nature of these infections. The hypothesis of Limoli et al. is that the conversion of P. aeruginosa to its mucoidy phenotype during chronic CF infection promotes coexistence by diminishing its ability to kill S. aureus. Highlighting a new facet of microbial interaction between two species that are traditionally thought of as competitors, this study provides a platform for studying community assembly in a relevant infection setting.Sophie E. DarchCarolyn B. IbbersonMarvin WhiteleyAmerican Society for MicrobiologyarticlePseudomonas aeruginosaStaphylococcus aureusaggregatesbiofilmscoinfectioncystic fibrosisMicrobiologyQR1-502ENmBio, Vol 8, Iss 3 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pseudomonas aeruginosa Staphylococcus aureus aggregates biofilms coinfection cystic fibrosis Microbiology QR1-502
spellingShingle	Pseudomonas aeruginosa Staphylococcus aureus aggregates biofilms coinfection cystic fibrosis Microbiology QR1-502 Sophie E. Darch Carolyn B. Ibberson Marvin Whiteley Evolution of Bacterial “Frenemies”
description	ABSTRACT Chronic polymicrobial infections are associated with increased virulence compared to monospecies infections. However, our understanding of microbial dynamics during polymicrobial infection is limited. A recent study by Limoli and colleagues (D. H. Limoli, G. B. Whitfield, T. Kitao, M. L. Ivey, M. R. Davis, Jr., et al., mBio 8:e00186-17, 2017, https://doi.org/10.1128/mBio.00186-17 ) provides insight into a mechanism that may contribute to the coexistence of Pseudomonas aeruginosa and Staphylococcus aureus in the cystic fibrosis (CF) lung. CF lung infections have frequently been used to investigate microbial interactions due to both the complex polymicrobial community and chronic nature of these infections. The hypothesis of Limoli et al. is that the conversion of P. aeruginosa to its mucoidy phenotype during chronic CF infection promotes coexistence by diminishing its ability to kill S. aureus. Highlighting a new facet of microbial interaction between two species that are traditionally thought of as competitors, this study provides a platform for studying community assembly in a relevant infection setting.
format	article
author	Sophie E. Darch Carolyn B. Ibberson Marvin Whiteley
author_facet	Sophie E. Darch Carolyn B. Ibberson Marvin Whiteley
author_sort	Sophie E. Darch
title	Evolution of Bacterial “Frenemies”
title_short	Evolution of Bacterial “Frenemies”
title_full	Evolution of Bacterial “Frenemies”
title_fullStr	Evolution of Bacterial “Frenemies”
title_full_unstemmed	Evolution of Bacterial “Frenemies”
title_sort	evolution of bacterial “frenemies”
publisher	American Society for Microbiology
publishDate	2017
url	https://doaj.org/article/dfd633706751468a949d0afcc7d7515b
work_keys_str_mv	AT sophieedarch evolutionofbacterialfrenemies AT carolynbibberson evolutionofbacterialfrenemies AT marvinwhiteley evolutionofbacterialfrenemies
_version_	1718427369533865984

Evolution of Bacterial “Frenemies”

Ejemplares similares