Cytochrome c: Using Biological Insight toward Engineering an Optimized Anticancer Biodrug

Cytochrome c: Using Biological Insight toward Engineering an Optimized Anticancer Biodrug

The heme protein cytochrome c (Cyt c) plays pivotal roles in cellular life and death processes. In the respiratory chain of mitochondria, it serves as an electron transfer protein, contributing to the proliferation of healthy cells. In the cell cytoplasm, it activates intrinsic apoptosis to terminat...

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Autores principales: Louis J. Delinois, Omar De León-Vélez, Adriana Vázquez-Medina, Alondra Vélez-Cabrera, Amanda Marrero-Sánchez, Christopher Nieves-Escobar, Daniela Alfonso-Cano, Delvin Caraballo-Rodríguez, Jael Rodriguez-Ortiz, Jemily Acosta-Mercado, Josué A. Benjamín-Rivera, Kiara González-González, Kysha Fernández-Adorno, Lisby Santiago-Pagán, Rafael Delgado-Vergara, Xaiomy Torres-Ávila, Andrea Maser-Figueroa, Gladimarys Grajales-Avilés, Glorimar I. Miranda Méndez, Javier Santiago-Pagán, Miguel Nieves-Santiago, Vanessa Álvarez-Carrillo, Kai Griebenow, Arthur D. Tinoco
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
cytochrome c
therapeutic proteins
smart drug delivery systems
intrinsic apoptosis
Inorganic chemistry
QD146-197
Acceso en línea:https://doaj.org/article/dfe1538b7c8849238d3ba678d4a463d2
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