Aptamer-enabled uptake of small molecule ligands

Abstract The relative ease of isolating aptamers with high specificity for target molecules suggests that molecular recognition may be common in the folds of natural RNAs. We show here that, when expressed in cells, aptamers can increase the intracellular concentrations of their small molecule ligan...

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Auteurs principaux: Supipi Liyamali Auwardt, Yeon-Jung Seo, Muslum Ilgu, Judhajeet Ray, Robert R. Feldges, Shambhavi Shubham, Lee Bendickson, Howard A. Levine, Marit Nilsen-Hamilton
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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R
Q
Accès en ligne:https://doaj.org/article/dfe7e4de04d0438488801b4f79c94ba4
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