Polymerization of C9 enhances bacterial cell envelope damage and killing by membrane attack complex pores
Complement proteins can form membrane attack complex (MAC) pores that directly kill Gram-negative bacteria. MAC pores assemble by stepwise binding of C5b, C6, C7, C8 and finally C9, which can polymerize into a transmembrane ring of up to 18 C9 monomers. It is still unclear if the assembly of a polym...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/dfe85b977e9f41b49d59a18f8b19cb34 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|