Polymerization of C9 enhances bacterial cell envelope damage and killing by membrane attack complex pores
Complement proteins can form membrane attack complex (MAC) pores that directly kill Gram-negative bacteria. MAC pores assemble by stepwise binding of C5b, C6, C7, C8 and finally C9, which can polymerize into a transmembrane ring of up to 18 C9 monomers. It is still unclear if the assembly of a polym...
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Public Library of Science (PLoS)
2021
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Acceso en línea: | https://doaj.org/article/dfe85b977e9f41b49d59a18f8b19cb34 |
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por Dennis J Doorduijn, Dani A C Heesterbeek, Maartje Ruyken, Carla J C de Haas, Daphne A C Stapels, Piet C Aerts, Suzan H M Rooijakkers, Bart W Bardoel
Publicado 2021
Enlace del recursoPublicado 2021
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