Interaction of Lipocalin 2, Transferrin, and Siderophores Determines the Replicative Niche of <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> during Pneumonia
ABSTRACT Pathogenic bacteria require iron for replication within their host. Klebsiella pneumoniae and other Gram-negative pathogens produce the prototypical siderophore enterobactin (Ent) to scavenge iron in vivo. In response, mucosal surfaces secrete lipocalin 2 (Lcn2), an innate immune protein th...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2012
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| Accès en ligne: | https://doaj.org/article/dfeb1f64b943409081300028f398ff99 |
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