Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma

Trevor Hughes,1 Matthew Traynor2 1Brigham Young University, Rexburg, ID, USA; 2Premier Eye Care of Eastern Idaho, Idaho Falls, ID, USACorrespondence: Matthew TraynorPremier Eye Care of Eastern Idaho, Idaho Falls, ID, USATel +1 208 529-6600Email doctortraynor@gmail.comPurpose: To report treatment out...

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Autores principales:	Hughes T, Traynor M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	ab interno canaloplasty migs open angle glaucoma visco360 omni glaucoma surgery viscodilation Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/dffe2f008fa94e418415ab2224c4fb39
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spelling	oai:doaj.org-article:dffe2f008fa94e418415ab2224c4fb392021-12-02T11:38:23ZClinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma1177-5483https://doaj.org/article/dffe2f008fa94e418415ab2224c4fb392020-10-01T00:00:00Zhttps://www.dovepress.com/clinical-results-of-ab-interno-canaloplasty-in-patients-with-open-angl-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Trevor Hughes,1 Matthew Traynor2 1Brigham Young University, Rexburg, ID, USA; 2Premier Eye Care of Eastern Idaho, Idaho Falls, ID, USACorrespondence: Matthew TraynorPremier Eye Care of Eastern Idaho, Idaho Falls, ID, USATel +1 208 529-6600Email doctortraynor@gmail.comPurpose: To report treatment outcomes of ab interno canaloplasty using the Visco360 and Omni system devices as a standalone procedure or combined with cataract surgery in patients with open-angle glaucoma (OAG).Design: Retrospective, single-center, consecutive case series.Study Patients: Eighty-nine eyes of 64 patients aged 43 to 91 with open-angle glaucoma treated with ab interno canaloplasty between January 2018 and September 2019. Eyes with previous incisional glaucoma surgery and eyes with less than 90 degrees of viscodilation were excluded.Intervention: Patients underwent ab interno canaloplasty as a stand-alone procedure or in conjunction with cataract surgery. Ab interno canaloplasty was performed with either the Visco360 or Omni System devices (Sight Sciences, Menlo Park, CA). Treatment consisted of viscodilation without trabeculotomy.Main Outcome Measures: Primary outcome measures were mean IOP and mean number of glaucoma medications. Additional analysis included the impact of degrees of treatment on treatment outcomes.Results: Preoperative mean IOP was 24.5 ± 8.3; the number of preoperative glaucoma medications was 2.5 ± 1.3. At 18 months postoperative, the mean IOP was reduced 36% to 15.8 ± 2.5 (P< 0.001) and glaucoma medications were reduced 32% to 1.7 ± 1.5 (P< 0.05). Higher preoperative IOP was significantly correlated with increased IOP lowering. Reduction of mean IOP and medications were not significantly different between standalone ab interno canaloplasty vs cataract surgery/ab interno canaloplasty. Reduction of mean IOP and medications were not significantly different between patients with 180 degrees of treatment vs 360 degrees of treatment.Conclusion: Ab interno canaloplasty reduces IOP and glaucoma medication use in patients with OAG whether as a standalone surgery or in combination with cataract surgery.Keywords: ab interno, canaloplasty, MIGS, open angle glaucoma, Visco360, Omni, glaucoma surgery, viscodilationHughes TTraynor MDove Medical Pressarticleab internocanaloplastymigsopen angle glaucomavisco360omniglaucoma surgeryviscodilationOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 3641-3650 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	ab interno canaloplasty migs open angle glaucoma visco360 omni glaucoma surgery viscodilation Ophthalmology RE1-994
spellingShingle	ab interno canaloplasty migs open angle glaucoma visco360 omni glaucoma surgery viscodilation Ophthalmology RE1-994 Hughes T Traynor M Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma
description	Trevor Hughes,1 Matthew Traynor2 1Brigham Young University, Rexburg, ID, USA; 2Premier Eye Care of Eastern Idaho, Idaho Falls, ID, USACorrespondence: Matthew TraynorPremier Eye Care of Eastern Idaho, Idaho Falls, ID, USATel +1 208 529-6600Email doctortraynor@gmail.comPurpose: To report treatment outcomes of ab interno canaloplasty using the Visco360 and Omni system devices as a standalone procedure or combined with cataract surgery in patients with open-angle glaucoma (OAG).Design: Retrospective, single-center, consecutive case series.Study Patients: Eighty-nine eyes of 64 patients aged 43 to 91 with open-angle glaucoma treated with ab interno canaloplasty between January 2018 and September 2019. Eyes with previous incisional glaucoma surgery and eyes with less than 90 degrees of viscodilation were excluded.Intervention: Patients underwent ab interno canaloplasty as a stand-alone procedure or in conjunction with cataract surgery. Ab interno canaloplasty was performed with either the Visco360 or Omni System devices (Sight Sciences, Menlo Park, CA). Treatment consisted of viscodilation without trabeculotomy.Main Outcome Measures: Primary outcome measures were mean IOP and mean number of glaucoma medications. Additional analysis included the impact of degrees of treatment on treatment outcomes.Results: Preoperative mean IOP was 24.5 ± 8.3; the number of preoperative glaucoma medications was 2.5 ± 1.3. At 18 months postoperative, the mean IOP was reduced 36% to 15.8 ± 2.5 (P< 0.001) and glaucoma medications were reduced 32% to 1.7 ± 1.5 (P< 0.05). Higher preoperative IOP was significantly correlated with increased IOP lowering. Reduction of mean IOP and medications were not significantly different between standalone ab interno canaloplasty vs cataract surgery/ab interno canaloplasty. Reduction of mean IOP and medications were not significantly different between patients with 180 degrees of treatment vs 360 degrees of treatment.Conclusion: Ab interno canaloplasty reduces IOP and glaucoma medication use in patients with OAG whether as a standalone surgery or in combination with cataract surgery.Keywords: ab interno, canaloplasty, MIGS, open angle glaucoma, Visco360, Omni, glaucoma surgery, viscodilation
format	article
author	Hughes T Traynor M
author_facet	Hughes T Traynor M
author_sort	Hughes T
title	Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma
title_short	Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma
title_full	Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma
title_fullStr	Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma
title_full_unstemmed	Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma
title_sort	clinical results of ab interno canaloplasty in patients with open-angle glaucoma
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/dffe2f008fa94e418415ab2224c4fb39
work_keys_str_mv	AT hughest clinicalresultsofabinternocanaloplastyinpatientswithopenangleglaucoma AT traynorm clinicalresultsofabinternocanaloplastyinpatientswithopenangleglaucoma
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Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma

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