The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling

INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps)  in INO80, showing that Arp8 and Arp4 module sense the DNA length separating...

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Autores principales: Sandipan Brahma, Mzwanele Ngubo, Somnath Paul, Maheshi Udugama, Blaine Bartholomew
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/e00fc131e6374772ad0cb36e70283b47
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spelling oai:doaj.org-article:e00fc131e6374772ad0cb36e70283b472021-12-02T14:39:43ZThe Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling10.1038/s41467-018-05710-72041-1723https://doaj.org/article/e00fc131e6374772ad0cb36e70283b472018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05710-7https://doaj.org/toc/2041-1723INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps)  in INO80, showing that Arp8 and Arp4 module sense the DNA length separating nucleosomes and regulate nucleosome remodeling.Sandipan BrahmaMzwanele NguboSomnath PaulMaheshi UdugamaBlaine BartholomewNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sandipan Brahma
Mzwanele Ngubo
Somnath Paul
Maheshi Udugama
Blaine Bartholomew
The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
description INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps)  in INO80, showing that Arp8 and Arp4 module sense the DNA length separating nucleosomes and regulate nucleosome remodeling.
format article
author Sandipan Brahma
Mzwanele Ngubo
Somnath Paul
Maheshi Udugama
Blaine Bartholomew
author_facet Sandipan Brahma
Mzwanele Ngubo
Somnath Paul
Maheshi Udugama
Blaine Bartholomew
author_sort Sandipan Brahma
title The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
title_short The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
title_full The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
title_fullStr The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
title_full_unstemmed The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
title_sort arp8 and arp4 module acts as a dna sensor controlling ino80 chromatin remodeling
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/e00fc131e6374772ad0cb36e70283b47
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