The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps) in INO80, showing that Arp8 and Arp4 module sense the DNA length separating...
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Nature Portfolio
2018
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oai:doaj.org-article:e00fc131e6374772ad0cb36e70283b472021-12-02T14:39:43ZThe Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling10.1038/s41467-018-05710-72041-1723https://doaj.org/article/e00fc131e6374772ad0cb36e70283b472018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05710-7https://doaj.org/toc/2041-1723INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps) in INO80, showing that Arp8 and Arp4 module sense the DNA length separating nucleosomes and regulate nucleosome remodeling.Sandipan BrahmaMzwanele NguboSomnath PaulMaheshi UdugamaBlaine BartholomewNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q Sandipan Brahma Mzwanele Ngubo Somnath Paul Maheshi Udugama Blaine Bartholomew The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling |
description |
INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps) in INO80, showing that Arp8 and Arp4 module sense the DNA length separating nucleosomes and regulate nucleosome remodeling. |
format |
article |
author |
Sandipan Brahma Mzwanele Ngubo Somnath Paul Maheshi Udugama Blaine Bartholomew |
author_facet |
Sandipan Brahma Mzwanele Ngubo Somnath Paul Maheshi Udugama Blaine Bartholomew |
author_sort |
Sandipan Brahma |
title |
The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling |
title_short |
The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling |
title_full |
The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling |
title_fullStr |
The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling |
title_full_unstemmed |
The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling |
title_sort |
arp8 and arp4 module acts as a dna sensor controlling ino80 chromatin remodeling |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/e00fc131e6374772ad0cb36e70283b47 |
work_keys_str_mv |
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