Genome-wide discovery of hidden genes mediating known drug-disease association using KDDANet
Abstract Many of genes mediating Known Drug-Disease Association (KDDA) are escaped from experimental detection. Identifying of these genes (hidden genes) is of great significance for understanding disease pathogenesis and guiding drug repurposing. Here, we presented a novel computational tool, calle...
Guardado en:
Autores principales: | Hua Yu, Lu Lu, Ming Chen, Chen Li, Jin Zhang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e014127581934eada7759bad1f929a14 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.
por: Farida S Akhtari, et al.
Publicado: (2021) -
Discovery of photosynthesis genes through whole-genome sequencing of acetate-requiring mutants of Chlamydomonas reinhardtii.
por: Setsuko Wakao, et al.
Publicado: (2021) -
A genome-wide association study of hypertension and blood pressure in African Americans.
por: Adebowale Adeyemo, et al.
Publicado: (2009) -
Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.
por: Erin N Smith, et al.
Publicado: (2011) -
Genome-wide association studies of the PR interval in African Americans.
por: J Gustav Smith, et al.
Publicado: (2011)