STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods

STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods

Abstract The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis. In these applications, target cells are extremely rare and fragile in peripheral circulation, which makes the genetic analy...

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Autores principales: Ann-Sophie Vander Plaetsen, Lieselot Deleye, Senne Cornelis, Laurentijn Tilleman, Filip Van Nieuwerburgh, Dieter Deforce
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e01b2b8da70542ac943ce8b4e70398e9
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