A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses

Understanding virus assembly could identify potential drug targets. Here the authors use a safe and efficient method to solve pathogenic flavivirus structures, revealing two lipid-like ligands within highly conserved pockets of the stem region of envelope protein that are important for virus maturat...

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Autores principales: Joshua M. Hardy, Natalee D. Newton, Naphak Modhiran, Connor A. P. Scott, Hariprasad Venugopal, Laura J. Vet, Paul R. Young, Roy A. Hall, Jody Hobson-Peters, Fasséli Coulibaly, Daniel Watterson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e01baa3c70744276b2e3dffa7df9e256
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