A man-made ATP-binding protein evolved independent of nature causes abnormal growth in bacterial cells.

Recent advances in de novo protein evolution have made it possible to create synthetic proteins from unbiased libraries that fold into stable tertiary structures with predefined functions. However, it is not known whether such proteins will be functional when expressed inside living cells or how a h...

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Bibliographic Details
Main Authors: Joshua M Stomel, James W Wilson, Megan A León, Phillip Stafford, John C Chaput
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
R
Q
Online Access:https://doaj.org/article/e0215494bed24e8781ac1772fa2da4c3
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