Comparison of Enoxaparin and Rivaroxaban in the Prophylaxis of Deep Venous Thrombosis in Arthroplasty

Background. Pulmonary embolism is a serious early complication of arthroplasty procedures that can develop after deep venous thrombosis. The present study aimed to compare rivaroxaban and enoxaparin in terms of preventing DV and PE, and also in this study, we compared the complications due to these...

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Autores principales: Necati Çiçek, İsmail Ağir, Hacı Bayram Tosun, Abuzer Uludağ, Abdulkadir Sari
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Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/e02581443d3a48b08e96ef81985ac2a0
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spelling oai:doaj.org-article:e02581443d3a48b08e96ef81985ac2a02021-11-29T00:55:45ZComparison of Enoxaparin and Rivaroxaban in the Prophylaxis of Deep Venous Thrombosis in Arthroplasty2090-285910.1155/2021/2945978https://doaj.org/article/e02581443d3a48b08e96ef81985ac2a02021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2945978https://doaj.org/toc/2090-2859Background. Pulmonary embolism is a serious early complication of arthroplasty procedures that can develop after deep venous thrombosis. The present study aimed to compare rivaroxaban and enoxaparin in terms of preventing DV and PE, and also in this study, we compared the complications due to these drugs in patients undergoing elective arthroplasty. Materials and Methods. 214 patients were divided into three groups based on their treatment regimens. In group I, enoxaparin was used, in group II, rivaroxaban was used, and in group III, enoxaparin was used throughout hospitalization, and after hospital discharge, rivaroxaban was used. These three groups were compared according to the occurrence of deep venous thrombosis, pulmonary embolism, and major and minor complications. Results. Major postoperative complications occurred in 5, 15, and 6 patients in group I, II, and III, respectively. Minor postoperative complications occurred in 10, 24, and 11 patients in group I, II, and III, respectively. No significant difference was found among the three groups. Deep venous thrombosis or pulmonary embolism was not observed in any patient. Conclusion. Rivaroxaban was found to be as effective as enoxaparin in the prevention of deep venous thrombosis and other complications after arthroplasty. Moreover, oral rivaroxaban provided greater ease of use compared to subcutaneous enoxaparin. Based on these findings, we consider that rivaroxaban could be an effective alternative to enoxaparin.Necati Çiçekİsmail AğirHacı Bayram TosunAbuzer UludağAbdulkadir SariHindawi LimitedarticleMedical emergencies. Critical care. Intensive care. First aidRC86-88.9ENEmergency Medicine International, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
spellingShingle Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Necati Çiçek
İsmail Ağir
Hacı Bayram Tosun
Abuzer Uludağ
Abdulkadir Sari
Comparison of Enoxaparin and Rivaroxaban in the Prophylaxis of Deep Venous Thrombosis in Arthroplasty
description Background. Pulmonary embolism is a serious early complication of arthroplasty procedures that can develop after deep venous thrombosis. The present study aimed to compare rivaroxaban and enoxaparin in terms of preventing DV and PE, and also in this study, we compared the complications due to these drugs in patients undergoing elective arthroplasty. Materials and Methods. 214 patients were divided into three groups based on their treatment regimens. In group I, enoxaparin was used, in group II, rivaroxaban was used, and in group III, enoxaparin was used throughout hospitalization, and after hospital discharge, rivaroxaban was used. These three groups were compared according to the occurrence of deep venous thrombosis, pulmonary embolism, and major and minor complications. Results. Major postoperative complications occurred in 5, 15, and 6 patients in group I, II, and III, respectively. Minor postoperative complications occurred in 10, 24, and 11 patients in group I, II, and III, respectively. No significant difference was found among the three groups. Deep venous thrombosis or pulmonary embolism was not observed in any patient. Conclusion. Rivaroxaban was found to be as effective as enoxaparin in the prevention of deep venous thrombosis and other complications after arthroplasty. Moreover, oral rivaroxaban provided greater ease of use compared to subcutaneous enoxaparin. Based on these findings, we consider that rivaroxaban could be an effective alternative to enoxaparin.
format article
author Necati Çiçek
İsmail Ağir
Hacı Bayram Tosun
Abuzer Uludağ
Abdulkadir Sari
author_facet Necati Çiçek
İsmail Ağir
Hacı Bayram Tosun
Abuzer Uludağ
Abdulkadir Sari
author_sort Necati Çiçek
title Comparison of Enoxaparin and Rivaroxaban in the Prophylaxis of Deep Venous Thrombosis in Arthroplasty
title_short Comparison of Enoxaparin and Rivaroxaban in the Prophylaxis of Deep Venous Thrombosis in Arthroplasty
title_full Comparison of Enoxaparin and Rivaroxaban in the Prophylaxis of Deep Venous Thrombosis in Arthroplasty
title_fullStr Comparison of Enoxaparin and Rivaroxaban in the Prophylaxis of Deep Venous Thrombosis in Arthroplasty
title_full_unstemmed Comparison of Enoxaparin and Rivaroxaban in the Prophylaxis of Deep Venous Thrombosis in Arthroplasty
title_sort comparison of enoxaparin and rivaroxaban in the prophylaxis of deep venous thrombosis in arthroplasty
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/e02581443d3a48b08e96ef81985ac2a0
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