ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions.
We describe a web tool ENZO (Enzyme Kinetics), a graphical interface for building kinetic models of enzyme catalyzed reactions. ENZO automatically generates the corresponding differential equations from a stipulated enzyme reaction scheme. These differential equations are processed by a numerical so...
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2011
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oai:doaj.org-article:e027394a2db2484893dde545c2a8c00b2021-11-18T06:49:56ZENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions.1932-620310.1371/journal.pone.0022265https://doaj.org/article/e027394a2db2484893dde545c2a8c00b2011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21818304/?tool=EBIhttps://doaj.org/toc/1932-6203We describe a web tool ENZO (Enzyme Kinetics), a graphical interface for building kinetic models of enzyme catalyzed reactions. ENZO automatically generates the corresponding differential equations from a stipulated enzyme reaction scheme. These differential equations are processed by a numerical solver and a regression algorithm which fits the coefficients of differential equations to experimentally observed time course curves. ENZO allows rapid evaluation of rival reaction schemes and can be used for routine tests in enzyme kinetics. It is freely available as a web tool, at http://enzo.cmm.ki.si.Staš BevcJanez KoncJure StojanMilan HodoščekMatej PencaMatej PraprotnikDušanka JanežičPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 7, p e22265 (2011) |
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Medicine R Science Q |
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Medicine R Science Q Staš Bevc Janez Konc Jure Stojan Milan Hodošček Matej Penca Matej Praprotnik Dušanka Janežič ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions. |
| description |
We describe a web tool ENZO (Enzyme Kinetics), a graphical interface for building kinetic models of enzyme catalyzed reactions. ENZO automatically generates the corresponding differential equations from a stipulated enzyme reaction scheme. These differential equations are processed by a numerical solver and a regression algorithm which fits the coefficients of differential equations to experimentally observed time course curves. ENZO allows rapid evaluation of rival reaction schemes and can be used for routine tests in enzyme kinetics. It is freely available as a web tool, at http://enzo.cmm.ki.si. |
| format |
article |
| author |
Staš Bevc Janez Konc Jure Stojan Milan Hodošček Matej Penca Matej Praprotnik Dušanka Janežič |
| author_facet |
Staš Bevc Janez Konc Jure Stojan Milan Hodošček Matej Penca Matej Praprotnik Dušanka Janežič |
| author_sort |
Staš Bevc |
| title |
ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions. |
| title_short |
ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions. |
| title_full |
ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions. |
| title_fullStr |
ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions. |
| title_full_unstemmed |
ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions. |
| title_sort |
enzo: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2011 |
| url |
https://doaj.org/article/e027394a2db2484893dde545c2a8c00b |
| work_keys_str_mv |
AT stasbevc enzoawebtoolforderivationandevaluationofkineticmodelsofenzymecatalyzedreactions AT janezkonc enzoawebtoolforderivationandevaluationofkineticmodelsofenzymecatalyzedreactions AT jurestojan enzoawebtoolforderivationandevaluationofkineticmodelsofenzymecatalyzedreactions AT milanhodoscek enzoawebtoolforderivationandevaluationofkineticmodelsofenzymecatalyzedreactions AT matejpenca enzoawebtoolforderivationandevaluationofkineticmodelsofenzymecatalyzedreactions AT matejpraprotnik enzoawebtoolforderivationandevaluationofkineticmodelsofenzymecatalyzedreactions AT dusankajanezic enzoawebtoolforderivationandevaluationofkineticmodelsofenzymecatalyzedreactions |
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1718424385928298496 |