Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans
The mechanisms of paternal epigenetic inheritance and its influence on offspring are still poorly understood. Here the authors provide evidence that in C. elegans, sperm-inherited chromatin states influence transcription and cell identity in the germ cells of offspring.
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Nature Portfolio
2019
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oai:doaj.org-article:e02cbda0c517410b95ec75cecfc44be82021-12-02T14:39:19ZSperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans10.1038/s41467-019-09141-w2041-1723https://doaj.org/article/e02cbda0c517410b95ec75cecfc44be82019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09141-whttps://doaj.org/toc/2041-1723The mechanisms of paternal epigenetic inheritance and its influence on offspring are still poorly understood. Here the authors provide evidence that in C. elegans, sperm-inherited chromatin states influence transcription and cell identity in the germ cells of offspring.Kiyomi Raye KaneshiroAndreas RechtsteinerSusan StromeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
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Science Q Kiyomi Raye Kaneshiro Andreas Rechtsteiner Susan Strome Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans |
description |
The mechanisms of paternal epigenetic inheritance and its influence on offspring are still poorly understood. Here the authors provide evidence that in C. elegans, sperm-inherited chromatin states influence transcription and cell identity in the germ cells of offspring. |
format |
article |
author |
Kiyomi Raye Kaneshiro Andreas Rechtsteiner Susan Strome |
author_facet |
Kiyomi Raye Kaneshiro Andreas Rechtsteiner Susan Strome |
author_sort |
Kiyomi Raye Kaneshiro |
title |
Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans |
title_short |
Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans |
title_full |
Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans |
title_fullStr |
Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans |
title_full_unstemmed |
Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans |
title_sort |
sperm-inherited h3k27me3 impacts offspring transcription and development in c. elegans |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/e02cbda0c517410b95ec75cecfc44be8 |
work_keys_str_mv |
AT kiyomirayekaneshiro sperminheritedh3k27me3impactsoffspringtranscriptionanddevelopmentincelegans AT andreasrechtsteiner sperminheritedh3k27me3impactsoffspringtranscriptionanddevelopmentincelegans AT susanstrome sperminheritedh3k27me3impactsoffspringtranscriptionanddevelopmentincelegans |
_version_ |
1718390685597433856 |