Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans

The mechanisms of paternal epigenetic inheritance and its influence on offspring are still poorly understood. Here the authors provide evidence that in C. elegans, sperm-inherited chromatin states influence transcription and cell identity in the germ cells of offspring.

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Autores principales: Kiyomi Raye Kaneshiro, Andreas Rechtsteiner, Susan Strome
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e02cbda0c517410b95ec75cecfc44be8
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spelling oai:doaj.org-article:e02cbda0c517410b95ec75cecfc44be82021-12-02T14:39:19ZSperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans10.1038/s41467-019-09141-w2041-1723https://doaj.org/article/e02cbda0c517410b95ec75cecfc44be82019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09141-whttps://doaj.org/toc/2041-1723The mechanisms of paternal epigenetic inheritance and its influence on offspring are still poorly understood. Here the authors provide evidence that in C. elegans, sperm-inherited chromatin states influence transcription and cell identity in the germ cells of offspring.Kiyomi Raye KaneshiroAndreas RechtsteinerSusan StromeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kiyomi Raye Kaneshiro
Andreas Rechtsteiner
Susan Strome
Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans
description The mechanisms of paternal epigenetic inheritance and its influence on offspring are still poorly understood. Here the authors provide evidence that in C. elegans, sperm-inherited chromatin states influence transcription and cell identity in the germ cells of offspring.
format article
author Kiyomi Raye Kaneshiro
Andreas Rechtsteiner
Susan Strome
author_facet Kiyomi Raye Kaneshiro
Andreas Rechtsteiner
Susan Strome
author_sort Kiyomi Raye Kaneshiro
title Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans
title_short Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans
title_full Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans
title_fullStr Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans
title_full_unstemmed Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans
title_sort sperm-inherited h3k27me3 impacts offspring transcription and development in c. elegans
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e02cbda0c517410b95ec75cecfc44be8
work_keys_str_mv AT kiyomirayekaneshiro sperminheritedh3k27me3impactsoffspringtranscriptionanddevelopmentincelegans
AT andreasrechtsteiner sperminheritedh3k27me3impactsoffspringtranscriptionanddevelopmentincelegans
AT susanstrome sperminheritedh3k27me3impactsoffspringtranscriptionanddevelopmentincelegans
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