THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS

Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes toge...

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Autores principales: O. V. Logvinenko, C. L. Rakitinа, D. G. Ponomarenko, M. V. Kostychenko, N. S. Sarkisian, T. V. Berdnikova
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Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2014
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Acceso en línea:https://doaj.org/article/e02e836648ec4decbd62f3551e490a5e
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spelling oai:doaj.org-article:e02e836648ec4decbd62f3551e490a5e2021-11-22T07:09:46ZTHE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS2220-76192313-739810.15789/2220-7619-2013-3-275-278https://doaj.org/article/e02e836648ec4decbd62f3551e490a5e2014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/175https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.O. V. LogvinenkoC. L. RakitinаD. G. PonomarenkoM. V. KostychenkoN. S. SarkisianT. V. BerdnikovaSankt-Peterburg : NIIÈM imeni Pasteraarticlebrucellosislymphocyte subpopulationphagocytosisimmunoglobulinsnatural resistanceInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 3, Iss 3, Pp 275-278 (2014)
institution DOAJ
collection DOAJ
language RU
topic brucellosis
lymphocyte subpopulation
phagocytosis
immunoglobulins
natural resistance
Infectious and parasitic diseases
RC109-216
spellingShingle brucellosis
lymphocyte subpopulation
phagocytosis
immunoglobulins
natural resistance
Infectious and parasitic diseases
RC109-216
O. V. Logvinenko
C. L. Rakitinа
D. G. Ponomarenko
M. V. Kostychenko
N. S. Sarkisian
T. V. Berdnikova
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
description Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.
format article
author O. V. Logvinenko
C. L. Rakitinа
D. G. Ponomarenko
M. V. Kostychenko
N. S. Sarkisian
T. V. Berdnikova
author_facet O. V. Logvinenko
C. L. Rakitinа
D. G. Ponomarenko
M. V. Kostychenko
N. S. Sarkisian
T. V. Berdnikova
author_sort O. V. Logvinenko
title THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_short THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_full THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_fullStr THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_full_unstemmed THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_sort features of blood immunological parameters in patients with various forms of brucellosis
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2014
url https://doaj.org/article/e02e836648ec4decbd62f3551e490a5e
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