THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes toge...
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Sankt-Peterburg : NIIÈM imeni Pastera
2014
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oai:doaj.org-article:e02e836648ec4decbd62f3551e490a5e2021-11-22T07:09:46ZTHE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS2220-76192313-739810.15789/2220-7619-2013-3-275-278https://doaj.org/article/e02e836648ec4decbd62f3551e490a5e2014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/175https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.O. V. LogvinenkoC. L. RakitinаD. G. PonomarenkoM. V. KostychenkoN. S. SarkisianT. V. BerdnikovaSankt-Peterburg : NIIÈM imeni Pasteraarticlebrucellosislymphocyte subpopulationphagocytosisimmunoglobulinsnatural resistanceInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 3, Iss 3, Pp 275-278 (2014) |
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topic |
brucellosis lymphocyte subpopulation phagocytosis immunoglobulins natural resistance Infectious and parasitic diseases RC109-216 |
spellingShingle |
brucellosis lymphocyte subpopulation phagocytosis immunoglobulins natural resistance Infectious and parasitic diseases RC109-216 O. V. Logvinenko C. L. Rakitinа D. G. Ponomarenko M. V. Kostychenko N. S. Sarkisian T. V. Berdnikova THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
description |
Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy. |
format |
article |
author |
O. V. Logvinenko C. L. Rakitinа D. G. Ponomarenko M. V. Kostychenko N. S. Sarkisian T. V. Berdnikova |
author_facet |
O. V. Logvinenko C. L. Rakitinа D. G. Ponomarenko M. V. Kostychenko N. S. Sarkisian T. V. Berdnikova |
author_sort |
O. V. Logvinenko |
title |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_short |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_full |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_fullStr |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_full_unstemmed |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_sort |
features of blood immunological parameters in patients with various forms of brucellosis |
publisher |
Sankt-Peterburg : NIIÈM imeni Pastera |
publishDate |
2014 |
url |
https://doaj.org/article/e02e836648ec4decbd62f3551e490a5e |
work_keys_str_mv |
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