Potential Production of Theranostic Boron Nitride Nanotubes (<sup>64</sup>Cu-BNNTs) Radiolabeled by Neutron Capture

In this work, the radioisotope <sup>64</sup>Cu was obtained from copper (II) chloride dihydrate in a nuclear research reactor by neutron capture, (<sup>63</sup>Cu(n,γ)<sup>64</sup>Cu), and incorporated into boron nitride nanotubes (BNNTs) using a solvothermal proc...

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Autores principales: Wellington Marcos Silva, Helio Ribeiro, Jose Jaime Taha-Tijerina
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Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:e032c2310634417885f51baec07c57d82021-11-25T18:30:46ZPotential Production of Theranostic Boron Nitride Nanotubes (<sup>64</sup>Cu-BNNTs) Radiolabeled by Neutron Capture10.3390/nano111129072079-4991https://doaj.org/article/e032c2310634417885f51baec07c57d82021-10-01T00:00:00Zhttps://www.mdpi.com/2079-4991/11/11/2907https://doaj.org/toc/2079-4991In this work, the radioisotope <sup>64</sup>Cu was obtained from copper (II) chloride dihydrate in a nuclear research reactor by neutron capture, (<sup>63</sup>Cu(n,γ)<sup>64</sup>Cu), and incorporated into boron nitride nanotubes (BNNTs) using a solvothermal process. The produced <sup>64</sup>Cu-BNNTs were analyzed by TEM, MEV, FTIR, XDR, XPS and gamma spectrometry, with which it was possible to observe the formation of<sup>64</sup>Cu nanoparticles, with sizes of up to 16 nm, distributed through nanotubes. The synthesized of <sup>64</sup>Cu nanostructures showed a pure photoemission peak of 511 keV, which is characteristic of gamma radiation. This type of emission is desirable for Photon Emission Tomography (PET scan) image acquisition, as well as its use in several cancer treatments. Thus, <sup>64</sup>Cu-BNNTs present an excellent alternative as theranostic nanomaterials that can be used in diagnosis and therapy by different techniques used in nuclear medicine.Wellington Marcos SilvaHelio RibeiroJose Jaime Taha-TijerinaMDPI AGarticletheranostic nanomaterialsboron nitrideneutron capture reactionnuclear medicineChemistryQD1-999ENNanomaterials, Vol 11, Iss 2907, p 2907 (2021)
institution DOAJ
collection DOAJ
language EN
topic theranostic nanomaterials
boron nitride
neutron capture reaction
nuclear medicine
Chemistry
QD1-999
spellingShingle theranostic nanomaterials
boron nitride
neutron capture reaction
nuclear medicine
Chemistry
QD1-999
Wellington Marcos Silva
Helio Ribeiro
Jose Jaime Taha-Tijerina
Potential Production of Theranostic Boron Nitride Nanotubes (<sup>64</sup>Cu-BNNTs) Radiolabeled by Neutron Capture
description In this work, the radioisotope <sup>64</sup>Cu was obtained from copper (II) chloride dihydrate in a nuclear research reactor by neutron capture, (<sup>63</sup>Cu(n,γ)<sup>64</sup>Cu), and incorporated into boron nitride nanotubes (BNNTs) using a solvothermal process. The produced <sup>64</sup>Cu-BNNTs were analyzed by TEM, MEV, FTIR, XDR, XPS and gamma spectrometry, with which it was possible to observe the formation of<sup>64</sup>Cu nanoparticles, with sizes of up to 16 nm, distributed through nanotubes. The synthesized of <sup>64</sup>Cu nanostructures showed a pure photoemission peak of 511 keV, which is characteristic of gamma radiation. This type of emission is desirable for Photon Emission Tomography (PET scan) image acquisition, as well as its use in several cancer treatments. Thus, <sup>64</sup>Cu-BNNTs present an excellent alternative as theranostic nanomaterials that can be used in diagnosis and therapy by different techniques used in nuclear medicine.
format article
author Wellington Marcos Silva
Helio Ribeiro
Jose Jaime Taha-Tijerina
author_facet Wellington Marcos Silva
Helio Ribeiro
Jose Jaime Taha-Tijerina
author_sort Wellington Marcos Silva
title Potential Production of Theranostic Boron Nitride Nanotubes (<sup>64</sup>Cu-BNNTs) Radiolabeled by Neutron Capture
title_short Potential Production of Theranostic Boron Nitride Nanotubes (<sup>64</sup>Cu-BNNTs) Radiolabeled by Neutron Capture
title_full Potential Production of Theranostic Boron Nitride Nanotubes (<sup>64</sup>Cu-BNNTs) Radiolabeled by Neutron Capture
title_fullStr Potential Production of Theranostic Boron Nitride Nanotubes (<sup>64</sup>Cu-BNNTs) Radiolabeled by Neutron Capture
title_full_unstemmed Potential Production of Theranostic Boron Nitride Nanotubes (<sup>64</sup>Cu-BNNTs) Radiolabeled by Neutron Capture
title_sort potential production of theranostic boron nitride nanotubes (<sup>64</sup>cu-bnnts) radiolabeled by neutron capture
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/e032c2310634417885f51baec07c57d8
work_keys_str_mv AT wellingtonmarcossilva potentialproductionoftheranosticboronnitridenanotubessup64supcubnntsradiolabeledbyneutroncapture
AT helioribeiro potentialproductionoftheranosticboronnitridenanotubessup64supcubnntsradiolabeledbyneutroncapture
AT josejaimetahatijerina potentialproductionoftheranosticboronnitridenanotubessup64supcubnntsradiolabeledbyneutroncapture
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