Spatial dynamics of TB within a highly urbanised Asian metropolis using point patterns

Abstract Singapore is a high-income country in a region with a high prevalence of tuberculosis. The Singapore Tuberculosis (TB) Elimination Program (STEP) was set up in 1997, and the better surveillance and clinical management practices initiated under STEP led to a decade-long decline in the incide...

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Autores principales:	Sourav Das, Alex R. Cook, Win Wah, Khin Mar Kyi Win, Cynthia Bin Eng Chee, Yee Tang Wang, Li Yang Hsu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e038eb873a9940d190ac9f2849c20b7f
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spelling	oai:doaj.org-article:e038eb873a9940d190ac9f2849c20b7f2021-12-02T12:32:01ZSpatial dynamics of TB within a highly urbanised Asian metropolis using point patterns10.1038/s41598-017-00081-32045-2322https://doaj.org/article/e038eb873a9940d190ac9f2849c20b7f2017-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-00081-3https://doaj.org/toc/2045-2322Abstract Singapore is a high-income country in a region with a high prevalence of tuberculosis. The Singapore Tuberculosis (TB) Elimination Program (STEP) was set up in 1997, and the better surveillance and clinical management practices initiated under STEP led to a decade-long decline in the incidence levels. However, incidence rates started to rise again since 2008. The reasons for this rise are unclear. This study involved a spatial analysis of the epidemiology of TB among Singapore residents. More than 30 000 cases reported during 1995–2011 and their residential addresses were analysed for spatial risk and spatial clustering, using spatial point pattern methodology. The principal factor responsible for the increasing resident TB incidence in Singapore is the changing age profile of the population. In particular the burgeoning population aged above 65 years accounts for the increase in reported cases. Singapore’s population has one of the world’s lowest fertility and mortality rates, and the elderly population is projected to grow substantially over the next few decades. Tuberculosis rates may therefore continue to rise even with static or improving case management and surveillance.Sourav DasAlex R. CookWin WahKhin Mar Kyi WinCynthia Bin Eng CheeYee Tang WangLi Yang HsuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sourav Das Alex R. Cook Win Wah Khin Mar Kyi Win Cynthia Bin Eng Chee Yee Tang Wang Li Yang Hsu Spatial dynamics of TB within a highly urbanised Asian metropolis using point patterns
description	Abstract Singapore is a high-income country in a region with a high prevalence of tuberculosis. The Singapore Tuberculosis (TB) Elimination Program (STEP) was set up in 1997, and the better surveillance and clinical management practices initiated under STEP led to a decade-long decline in the incidence levels. However, incidence rates started to rise again since 2008. The reasons for this rise are unclear. This study involved a spatial analysis of the epidemiology of TB among Singapore residents. More than 30 000 cases reported during 1995–2011 and their residential addresses were analysed for spatial risk and spatial clustering, using spatial point pattern methodology. The principal factor responsible for the increasing resident TB incidence in Singapore is the changing age profile of the population. In particular the burgeoning population aged above 65 years accounts for the increase in reported cases. Singapore’s population has one of the world’s lowest fertility and mortality rates, and the elderly population is projected to grow substantially over the next few decades. Tuberculosis rates may therefore continue to rise even with static or improving case management and surveillance.
format	article
author	Sourav Das Alex R. Cook Win Wah Khin Mar Kyi Win Cynthia Bin Eng Chee Yee Tang Wang Li Yang Hsu
author_facet	Sourav Das Alex R. Cook Win Wah Khin Mar Kyi Win Cynthia Bin Eng Chee Yee Tang Wang Li Yang Hsu
author_sort	Sourav Das
title	Spatial dynamics of TB within a highly urbanised Asian metropolis using point patterns
title_short	Spatial dynamics of TB within a highly urbanised Asian metropolis using point patterns
title_full	Spatial dynamics of TB within a highly urbanised Asian metropolis using point patterns
title_fullStr	Spatial dynamics of TB within a highly urbanised Asian metropolis using point patterns
title_full_unstemmed	Spatial dynamics of TB within a highly urbanised Asian metropolis using point patterns
title_sort	spatial dynamics of tb within a highly urbanised asian metropolis using point patterns
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e038eb873a9940d190ac9f2849c20b7f
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_version_	1718394248699576320

Spatial dynamics of TB within a highly urbanised Asian metropolis using point patterns

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