Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A.

Neuropilin-1 (Nrp1) guides the development of the nervous and vascular systems, but its role in the mature brain remains to be explored. Here we report that the expression of the 65 kDa isoform of Sema3A, the ligand of Nrp1, by adult vascular endothelial cells, is regulated during the ovarian cycle...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Paolo Giacobini, Jyoti Parkash, Céline Campagne, Andrea Messina, Filippo Casoni, Charlotte Vanacker, Fanny Langlet, Barbara Hobo, Gabriella Cagnoni, Sarah Gallet, Naresh Kumar Hanchate, Danièle Mazur, Masahiko Taniguchi, Massimiliano Mazzone, Joost Verhaagen, Philippe Ciofi, Sébastien G Bouret, Luca Tamagnone, Vincent Prevot
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
Sujets:
Accès en ligne:https://doaj.org/article/e03a0204fd6c4ff899ff4801bc03f5d9
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!