Estimation of reproductive toxicity of the complex plant remedy "Tireoton"
To study the probable negative influence of the complex remedy "Tireoton" on the reproductive function of the laboratory animals the following tests have been carried out, namely the probable occurrence of embryo-toxicity, teratogenicity, foetotoxicity and its influence on the postnatal de...
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Scientific Сentre for Family Health and Human Reproduction Problems
2016
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oai:doaj.org-article:e03da5ecdfe5427085a2223efa5747602021-11-23T06:14:34ZEstimation of reproductive toxicity of the complex plant remedy "Tireoton"2541-94202587-959610.12737/20618https://doaj.org/article/e03da5ecdfe5427085a2223efa5747602016-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/172https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596To study the probable negative influence of the complex remedy "Tireoton" on the reproductive function of the laboratory animals the following tests have been carried out, namely the probable occurrence of embryo-toxicity, teratogenicity, foetotoxicity and its influence on the postnatal development of the laboratory animals progeny. The experiments have been carried out of the white Wistar rats. It has been established that the "Tireoton" at the doses of 75 and 750 mg/kg has no embryotoxic, teratogenic and fetotoxical effect. The introduction of the "Tireoton" at the dose of 750 mg/kg since 6th to 19th day of pregnancy does not influence on the postnatal development of white rats progeny.Y. G. RazuvaevaS. M. NikolaevN. V. VerlanI. P. UbeevaV. V. AyusheevaScientific Сentre for Family Health and Human Reproduction Problemsarticlepotentilla alba lscutellaria baicalensis georgirhodiola rosea lcomplex plant remedypotentilla alba lscutellaria baicalensis georgirhodiola rosea lembryo-toxicityteratogenicityfoetotoxicitypostnatal developmentScienceQRUActa Biomedica Scientifica, Vol 1, Iss 2, Pp 60-63 (2016) |
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potentilla alba l scutellaria baicalensis georgi rhodiola rosea l complex plant remedy potentilla alba l scutellaria baicalensis georgi rhodiola rosea l embryo-toxicity teratogenicity foetotoxicity postnatal development Science Q |
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potentilla alba l scutellaria baicalensis georgi rhodiola rosea l complex plant remedy potentilla alba l scutellaria baicalensis georgi rhodiola rosea l embryo-toxicity teratogenicity foetotoxicity postnatal development Science Q Y. G. Razuvaeva S. M. Nikolaev N. V. Verlan I. P. Ubeeva V. V. Ayusheeva Estimation of reproductive toxicity of the complex plant remedy "Tireoton" |
description |
To study the probable negative influence of the complex remedy "Tireoton" on the reproductive function of the laboratory animals the following tests have been carried out, namely the probable occurrence of embryo-toxicity, teratogenicity, foetotoxicity and its influence on the postnatal development of the laboratory animals progeny. The experiments have been carried out of the white Wistar rats. It has been established that the "Tireoton" at the doses of 75 and 750 mg/kg has no embryotoxic, teratogenic and fetotoxical effect. The introduction of the "Tireoton" at the dose of 750 mg/kg since 6th to 19th day of pregnancy does not influence on the postnatal development of white rats progeny. |
format |
article |
author |
Y. G. Razuvaeva S. M. Nikolaev N. V. Verlan I. P. Ubeeva V. V. Ayusheeva |
author_facet |
Y. G. Razuvaeva S. M. Nikolaev N. V. Verlan I. P. Ubeeva V. V. Ayusheeva |
author_sort |
Y. G. Razuvaeva |
title |
Estimation of reproductive toxicity of the complex plant remedy "Tireoton" |
title_short |
Estimation of reproductive toxicity of the complex plant remedy "Tireoton" |
title_full |
Estimation of reproductive toxicity of the complex plant remedy "Tireoton" |
title_fullStr |
Estimation of reproductive toxicity of the complex plant remedy "Tireoton" |
title_full_unstemmed |
Estimation of reproductive toxicity of the complex plant remedy "Tireoton" |
title_sort |
estimation of reproductive toxicity of the complex plant remedy "tireoton" |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2016 |
url |
https://doaj.org/article/e03da5ecdfe5427085a2223efa574760 |
work_keys_str_mv |
AT ygrazuvaeva estimationofreproductivetoxicityofthecomplexplantremedytireoton AT smnikolaev estimationofreproductivetoxicityofthecomplexplantremedytireoton AT nvverlan estimationofreproductivetoxicityofthecomplexplantremedytireoton AT ipubeeva estimationofreproductivetoxicityofthecomplexplantremedytireoton AT vvayusheeva estimationofreproductivetoxicityofthecomplexplantremedytireoton |
_version_ |
1718417102998601728 |