Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand

In this study, metal complex of Copper(II) with a Schiff base derived from 2,2-dihydroxyindane-1,3-dione and 2-aminoethanoic acid were synthesized. The product are characterized by spectral methods. The antimicrobial activity was tested on reference bacterial strains and the antioxidant capacity was...

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Autores principales:	Emir Horozić, Merima Ibišević, Darja Husejnagić, Enida Karić, Nusreta Hasić, Amina Hajdarević
Formato:	article
Lenguaje:	EN
Publicado:	University of Brawijaya 2021
Materias:	imine complexes antioxidants antimicrobial activity Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/e03f68b451ed4f41929f94797256e0df
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spelling	oai:doaj.org-article:e03f68b451ed4f41929f94797256e0df2021-11-24T12:35:25ZSpectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand2302-46902541-0733https://doaj.org/article/e03f68b451ed4f41929f94797256e0df2021-08-01T00:00:00Zhttps://jpacr.ub.ac.id/index.php/jpacr/article/view/569/pdfhttps://doaj.org/toc/2302-4690https://doaj.org/toc/2541-0733In this study, metal complex of Copper(II) with a Schiff base derived from 2,2-dihydroxyindane-1,3-dione and 2-aminoethanoic acid were synthesized. The product are characterized by spectral methods. The antimicrobial activity was tested on reference bacterial strains and the antioxidant capacity was analyzed by using the DPPH and FRAP methods. The spectral data indicates that the Schiff base coordinates the Copper(II) as a tridentate ONO donor ligand. The compounds showed weaker antimicrobial activity on certain tested microorganisms. In vitro testing of antioxidant activity showed a significant reducing ability of the complex, as well as inhibitory activity against DPPH radicals.Emir HorozićMerima IbiševićDarja HusejnagićEnida KarićNusreta HasićAmina HajdarevićUniversity of Brawijayaarticleiminecomplexesantioxidantsantimicrobial activityChemistryQD1-999ENJournal of Pure and Applied Chemistry Research, Vol 10, Iss 2, Pp 159-164 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	imine complexes antioxidants antimicrobial activity Chemistry QD1-999
spellingShingle	imine complexes antioxidants antimicrobial activity Chemistry QD1-999 Emir Horozić Merima Ibišević Darja Husejnagić Enida Karić Nusreta Hasić Amina Hajdarević Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand
description	In this study, metal complex of Copper(II) with a Schiff base derived from 2,2-dihydroxyindane-1,3-dione and 2-aminoethanoic acid were synthesized. The product are characterized by spectral methods. The antimicrobial activity was tested on reference bacterial strains and the antioxidant capacity was analyzed by using the DPPH and FRAP methods. The spectral data indicates that the Schiff base coordinates the Copper(II) as a tridentate ONO donor ligand. The compounds showed weaker antimicrobial activity on certain tested microorganisms. In vitro testing of antioxidant activity showed a significant reducing ability of the complex, as well as inhibitory activity against DPPH radicals.
format	article
author	Emir Horozić Merima Ibišević Darja Husejnagić Enida Karić Nusreta Hasić Amina Hajdarević
author_facet	Emir Horozić Merima Ibišević Darja Husejnagić Enida Karić Nusreta Hasić Amina Hajdarević
author_sort	Emir Horozić
title	Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand
title_short	Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand
title_full	Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand
title_fullStr	Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand
title_full_unstemmed	Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand
title_sort	spectral analysis and in vitro biological activity of cu(ii) complex with tridentate ono schiff base ligand
publisher	University of Brawijaya
publishDate	2021
url	https://doaj.org/article/e03f68b451ed4f41929f94797256e0df
work_keys_str_mv	AT emirhorozic spectralanalysisandinvitrobiologicalactivityofcuiicomplexwithtridentateonoschiffbaseligand AT merimaibisevic spectralanalysisandinvitrobiologicalactivityofcuiicomplexwithtridentateonoschiffbaseligand AT darjahusejnagic spectralanalysisandinvitrobiologicalactivityofcuiicomplexwithtridentateonoschiffbaseligand AT enidakaric spectralanalysisandinvitrobiologicalactivityofcuiicomplexwithtridentateonoschiffbaseligand AT nusretahasic spectralanalysisandinvitrobiologicalactivityofcuiicomplexwithtridentateonoschiffbaseligand AT aminahajdarevic spectralanalysisandinvitrobiologicalactivityofcuiicomplexwithtridentateonoschiffbaseligand
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Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand

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