Haploinsufficiency of akt1 prolongs the lifespan of mice.

Haploinsufficiency of akt1 prolongs the lifespan of mice.

There is increasing evidence that nutrient-sensing machinery is critically involved in the regulation of aging. The insulin/insulin-like growth factor-1 signaling pathway is the best-characterized pathway with an influence on longevity in a variety of organisms, ranging from yeast to rodents. Reduce...

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Autores principales: Aika Nojima, Masakatsu Yamashita, Yohko Yoshida, Ippei Shimizu, Harumi Ichimiya, Naomi Kamimura, Yoshio Kobayashi, Shigeo Ohta, Naoaki Ishii, Tohru Minamino
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e04105dc4ed44a10b29229bac99f9b10
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