Visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis

Abstract The present study aimed to quantify and visualize the degenerative patterns of the distal tibia and fibula due to ankle osteoarthritis (OA). We analyzed differences in tibial and fibular surface deviation between sides of patients with unilateral varus ankle OA (medial talar tilt > 4°) b...

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Autores principales:	Hiroyuki Seki, Naomichi Ogihara, Tetsuro Kokubo, Takeo Nagura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e046e3a206ff4280abf9a6d9bc0bb6eb
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spelling	oai:doaj.org-article:e046e3a206ff4280abf9a6d9bc0bb6eb2021-11-08T10:53:41ZVisualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis10.1038/s41598-021-00874-72045-2322https://doaj.org/article/e046e3a206ff4280abf9a6d9bc0bb6eb2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-00874-7https://doaj.org/toc/2045-2322Abstract The present study aimed to quantify and visualize the degenerative patterns of the distal tibia and fibula due to ankle osteoarthritis (OA). We analyzed differences in tibial and fibular surface deviation between sides of patients with unilateral varus ankle OA (medial talar tilt > 4°) by registering each surface model to the mirror image of corresponding bone. Computed tomography images of both feet of 33 patients (OA: 22, control: 11) were examined. Statistically significant surface depression of approximately 2.5 mm on the anterior articular surface of the medial malleolus, and surface elevation of approximately 1 mm on the anterodistal edge of the tibiofibular joint and the lateral malleolus were observed in OA patients. These bone degenerations were found to be correlated with those on the other side of the ankle joint, the medial margin of the talar trochlea and the lateral articular surface of the talus, respectively. In contrast, the amount of bone depression on the plafond was smaller than previously anticipated. Such quantitative information about stereotypical patterns of bone degeneration in ankle OA would contribute to better understanding of the development of ankle OA and possible therapeutic interventions.Hiroyuki SekiNaomichi OgiharaTetsuro KokuboTakeo NaguraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hiroyuki Seki Naomichi Ogihara Tetsuro Kokubo Takeo Nagura Visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis
description	Abstract The present study aimed to quantify and visualize the degenerative patterns of the distal tibia and fibula due to ankle osteoarthritis (OA). We analyzed differences in tibial and fibular surface deviation between sides of patients with unilateral varus ankle OA (medial talar tilt > 4°) by registering each surface model to the mirror image of corresponding bone. Computed tomography images of both feet of 33 patients (OA: 22, control: 11) were examined. Statistically significant surface depression of approximately 2.5 mm on the anterior articular surface of the medial malleolus, and surface elevation of approximately 1 mm on the anterodistal edge of the tibiofibular joint and the lateral malleolus were observed in OA patients. These bone degenerations were found to be correlated with those on the other side of the ankle joint, the medial margin of the talar trochlea and the lateral articular surface of the talus, respectively. In contrast, the amount of bone depression on the plafond was smaller than previously anticipated. Such quantitative information about stereotypical patterns of bone degeneration in ankle OA would contribute to better understanding of the development of ankle OA and possible therapeutic interventions.
format	article
author	Hiroyuki Seki Naomichi Ogihara Tetsuro Kokubo Takeo Nagura
author_facet	Hiroyuki Seki Naomichi Ogihara Tetsuro Kokubo Takeo Nagura
author_sort	Hiroyuki Seki
title	Visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis
title_short	Visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis
title_full	Visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis
title_fullStr	Visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis
title_full_unstemmed	Visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis
title_sort	visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e046e3a206ff4280abf9a6d9bc0bb6eb
work_keys_str_mv	AT hiroyukiseki visualizationandquantificationofthedegenerativepatternofthedistaltibiaandfibulainunilateralvarusankleosteoarthritis AT naomichiogihara visualizationandquantificationofthedegenerativepatternofthedistaltibiaandfibulainunilateralvarusankleosteoarthritis AT tetsurokokubo visualizationandquantificationofthedegenerativepatternofthedistaltibiaandfibulainunilateralvarusankleosteoarthritis AT takeonagura visualizationandquantificationofthedegenerativepatternofthedistaltibiaandfibulainunilateralvarusankleosteoarthritis
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Visualization and quantification of the degenerative pattern of the distal tibia and fibula in unilateral varus ankle osteoarthritis

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