Identification and characterisation of the RalA-ERp57 interaction: evidence for GDI activity of ERp57.
RalA is a membrane-associated small GTPase that regulates vesicle trafficking. Here we identify a specific interaction between RalA and ERp57, an oxidoreductase and signalling protein. ERp57 bound specifically to the GDP-bound form of RalA, but not the GTP-bound form, and inhibited the dissociation...
Guardado en:
Autores principales: | Adam Brymora, Iain G Duggin, Leise A Berven, Ellen M van Dam, Basil D Roufogalis, Phillip J Robinson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/e0485c883f5c42108cfec9d7570c0ecf |
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