Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes

Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes

Barniol-Xicota and Verhelst investigate the usefulness of different maleic acid-based copolymers (xMAs) to solubilize membrane proteins within native-like lipid environments. They use bacterial and mammalian cell lines to study different polymer solubilisation efficiencies and focus on resultant pro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Marta Barniol-Xicota, Steven H. L. Verhelst
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/e04abed1f80245d8b1e11956b1dbd7d6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:e04abed1f80245d8b1e11956b1dbd7d6
record_format dspace
spelling oai:doaj.org-article:e04abed1f80245d8b1e11956b1dbd7d62021-12-02T14:03:44ZLipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes10.1038/s42003-021-01711-32399-3642https://doaj.org/article/e04abed1f80245d8b1e11956b1dbd7d62021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01711-3https://doaj.org/toc/2399-3642Barniol-Xicota and Verhelst investigate the usefulness of different maleic acid-based copolymers (xMAs) to solubilize membrane proteins within native-like lipid environments. They use bacterial and mammalian cell lines to study different polymer solubilisation efficiencies and focus on resultant protein content, protein-lipid ratio, and the lipid compositions obtained within the xMA nanoparticles.Marta Barniol-XicotaSteven H. L. VerhelstNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Marta Barniol-Xicota
Steven H. L. Verhelst
Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes
description Barniol-Xicota and Verhelst investigate the usefulness of different maleic acid-based copolymers (xMAs) to solubilize membrane proteins within native-like lipid environments. They use bacterial and mammalian cell lines to study different polymer solubilisation efficiencies and focus on resultant protein content, protein-lipid ratio, and the lipid compositions obtained within the xMA nanoparticles.
format article
author Marta Barniol-Xicota
Steven H. L. Verhelst
author_facet Marta Barniol-Xicota
Steven H. L. Verhelst
author_sort Marta Barniol-Xicota
title Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes
title_short Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes
title_full Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes
title_fullStr Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes
title_full_unstemmed Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes
title_sort lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e04abed1f80245d8b1e11956b1dbd7d6
work_keys_str_mv AT martabarniolxicota lipidomicandingelanalysisofmaleicacidcopolymernanodiscsrevealsdifferencesincompositionofsolubilizedmembranes
AT stevenhlverhelst lipidomicandingelanalysisofmaleicacidcopolymernanodiscsrevealsdifferencesincompositionofsolubilizedmembranes
_version_ 1718392114024284160

Ejemplares similares