Correlating chemical diversity with taxonomic distance for discovery of natural products in myxobacteria

It is thought that the chances for discovery of novel natural products increase by screening rare organisms. Here the authors analyse metabolites produced by over 2300 myxobacterial strains and, indeed, find a correlation between taxonomic distance and production of distinct secondary metabolite fam...

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Autores principales: Thomas Hoffmann, Daniel Krug, Nisa Bozkurt, Srikanth Duddela, Rolf Jansen, Ronald Garcia, Klaus Gerth, Heinrich Steinmetz, Rolf Müller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/e04d0d9067134cffaac70fff45d6321e
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Sumario:It is thought that the chances for discovery of novel natural products increase by screening rare organisms. Here the authors analyse metabolites produced by over 2300 myxobacterial strains and, indeed, find a correlation between taxonomic distance and production of distinct secondary metabolite families.