Trends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.

<h4>Background</h4>Schistosomiasis, also known as bilharzia, is a chronic parasitic blood fluke infection acquired through contact with contaminated surface water. The illness may be mild or can cause significant morbidity with potentially serious complications. Children and those living...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Liesl De Boni, Veerle Msimang, Alex De Voux, John Frean
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/e0559750c4e446a8abfd7f9e64bd4425
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e0559750c4e446a8abfd7f9e64bd4425
record_format	dspace
spelling	oai:doaj.org-article:e0559750c4e446a8abfd7f9e64bd44252021-12-02T20:24:06ZTrends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.1935-27271935-273510.1371/journal.pntd.0009669https://doaj.org/article/e0559750c4e446a8abfd7f9e64bd44252021-09-01T00:00:00Zhttps://doi.org/10.1371/journal.pntd.0009669https://doaj.org/toc/1935-2727https://doaj.org/toc/1935-2735<h4>Background</h4>Schistosomiasis, also known as bilharzia, is a chronic parasitic blood fluke infection acquired through contact with contaminated surface water. The illness may be mild or can cause significant morbidity with potentially serious complications. Children and those living in rural areas with limited access to piped water and services for healthcare are the most commonly infected. To address the prevalence of the disease in parts of South Africa (SA) effective national control measures are planned, but have not yet been implemented. This study aimed to estimate the prevalence and trends of public sector laboratory-confirmed schistosomiasis cases in SA over an eight-year (2011-2018) period, to inform future control measures.<h4>Methodology & principal findings</h4>This is a descriptive analysis of secondary data from the National Health Laboratory Service (NHLS). The study included all records of patients for whom microscopic examination detected Schistosoma species eggs in urine or stool specimens from January 2011 to December 2018. Crude estimates of the prevalence were calculated using national census mid-year provincial population estimates as denominators, and simple linear regression was used to analyse prevalence trends. A test rate ratio was developed to describe variations in testing volumes among different groups and to adjust prevalence estimates for testing variations. A total number of 135 627 schistosomiasis cases was analysed with the highest prevalence observed among males and individuals aged 5-19 years. We describe ongoing endemicity in the Eastern Cape Province, and indicate important differences in the testing between population groups.<h4>Conclusion</h4>While there was no overall change in the prevalence of schistosomiasis during the analysis period, an average of 36 people per 100 000 was infected annually. As such, this represents an opportunity to control the disease and improve quality of life of affected people. Laboratory-based surveillance is a useful method for reporting occurrence and evaluating future intervention programs where resources to implement active surveillance are limited.Liesl De BoniVeerle MsimangAlex De VouxJohn FreanPublic Library of Science (PLoS)articleArctic medicine. Tropical medicineRC955-962Public aspects of medicineRA1-1270ENPLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009669 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
spellingShingle	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Liesl De Boni Veerle Msimang Alex De Voux John Frean Trends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.
description	<h4>Background</h4>Schistosomiasis, also known as bilharzia, is a chronic parasitic blood fluke infection acquired through contact with contaminated surface water. The illness may be mild or can cause significant morbidity with potentially serious complications. Children and those living in rural areas with limited access to piped water and services for healthcare are the most commonly infected. To address the prevalence of the disease in parts of South Africa (SA) effective national control measures are planned, but have not yet been implemented. This study aimed to estimate the prevalence and trends of public sector laboratory-confirmed schistosomiasis cases in SA over an eight-year (2011-2018) period, to inform future control measures.<h4>Methodology & principal findings</h4>This is a descriptive analysis of secondary data from the National Health Laboratory Service (NHLS). The study included all records of patients for whom microscopic examination detected Schistosoma species eggs in urine or stool specimens from January 2011 to December 2018. Crude estimates of the prevalence were calculated using national census mid-year provincial population estimates as denominators, and simple linear regression was used to analyse prevalence trends. A test rate ratio was developed to describe variations in testing volumes among different groups and to adjust prevalence estimates for testing variations. A total number of 135 627 schistosomiasis cases was analysed with the highest prevalence observed among males and individuals aged 5-19 years. We describe ongoing endemicity in the Eastern Cape Province, and indicate important differences in the testing between population groups.<h4>Conclusion</h4>While there was no overall change in the prevalence of schistosomiasis during the analysis period, an average of 36 people per 100 000 was infected annually. As such, this represents an opportunity to control the disease and improve quality of life of affected people. Laboratory-based surveillance is a useful method for reporting occurrence and evaluating future intervention programs where resources to implement active surveillance are limited.
format	article
author	Liesl De Boni Veerle Msimang Alex De Voux John Frean
author_facet	Liesl De Boni Veerle Msimang Alex De Voux John Frean
author_sort	Liesl De Boni
title	Trends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.
title_short	Trends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.
title_full	Trends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.
title_fullStr	Trends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.
title_full_unstemmed	Trends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.
title_sort	trends in the prevalence of microscopically-confirmed schistosomiasis in the south african public health sector, 2011-2018.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/e0559750c4e446a8abfd7f9e64bd4425
work_keys_str_mv	AT liesldeboni trendsintheprevalenceofmicroscopicallyconfirmedschistosomiasisinthesouthafricanpublichealthsector20112018 AT veerlemsimang trendsintheprevalenceofmicroscopicallyconfirmedschistosomiasisinthesouthafricanpublichealthsector20112018 AT alexdevoux trendsintheprevalenceofmicroscopicallyconfirmedschistosomiasisinthesouthafricanpublichealthsector20112018 AT johnfrean trendsintheprevalenceofmicroscopicallyconfirmedschistosomiasisinthesouthafricanpublichealthsector20112018
_version_	1718374080715948032

Trends in the prevalence of microscopically-confirmed schistosomiasis in the South African public health sector, 2011-2018.

Ejemplares similares